Evidence map›Paper›PMID 34156597›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2022

Health-related quality of life and associated factors in HIV-positive transplant candidates and recipients from a HIV-positive donor.

Claire Juliet Martin, Elmi Muller, Demetre Labadarios, Frederick Johannes Veldman, Susanna Maria Kassier

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Claire Juliet MartinUniversity of Pretoria, Pretoria, Gauteng, South Africa. claire.martin@up.ac.za.
Elmi MullerDepartment of Surgery, University of Cape Town, Cape Town, Western Cape, South Africa.
Demetre LabadariosDepartment of Human Nutrition, Stellenbosch University, Stellenbosch, Western Cape, South Africa.
Frederick Johannes VeldmanSefako Makgatho Health Sciences University, Pretoria, Gauteng, South Africa.
Susanna Maria KassierUniversity of KwaZulu-Natal, Pietermaritzburg, KwaZulu-Natal, South Africa.
Sefako Makgatho Health Sciences University · ZAStellenbosch University · ZAUniversity of Cape Town · ZAUniversity of KwaZulu-Natal · ZAUniversity of Pretoria · ZA

Funding

Maximizing the success of HIV+ to HIV+ kidney transplantation in South AfricaU01AI152153 · NIAID · UNIVERSITY OF CAPE TOWN · PI MULLER, ELMI · 2020 to 2024
$900k
Halley Stott Grant 2015National Research Foundation 104599NIAID NIH HHS U01 AI152153South African Sugar Association 246
6 · The paper itself

Abstract

introductionHRQOL in transplant candidates and recipients who are also infected with HIV and are awaiting a kidney, or have received one from a HIV-positive donor, has not been previously investigated.

methodsThe HRQOL of 47 HIV-positive kidney transplant candidates and 21 recipients from HIV-positive donors was evaluated using the Short Form-36 (SF-36) and face to face interviews at baseline and at 6 months. The correlation between SF-36 scores and sociodemographic, clinical and nutritional factors was determined.

results68 patients completed the SF-36 at baseline and 6 months. Transplant candidates: transplant candidates had lower HRQOL than recipients. The main mental stressors were income, employment and waiting for a donor. Physical health complaints were body pain (BP) and fatigue. Pre-albumin and BMI was positively correlated with general health at baseline (r = 0.401, p = 0.031 and r = 0.338, p = 0.025). Besides a positive association with role physical (RP) and BP, albumin was associated with overall physical composite score (PCS) (r = 0.329, p = 0.024) at 6 months. Transplant recipients: Transplant recipients had high HRQOL scores in all domains. PCS was 53.8 ± 10.0 and 56.6 ± 6.5 at baseline and 6 months respectively. MCS was 51.3 ± 11.5 and 54.2 ± 8.5 at baseline and 6 months respectively. Albumin correlated positively with PCS (r = 0.464, p = 0.034) at 6 months and role emotional (RE) (r = 0.492, p = 0.024). Higher pre-albumin was associated with better RE and RP abilities and MCS (r = 0.495, p = 0.034). MAMC was associated with four domains of physical health and strongly correlated with PCS (r = 0.821, p = 0.000).

conclusionStrategies to improve HRQOL include ongoing social support, assistance with employment issues and optimising nutritional status.

Indexed as

HIV InfectionsKidney TransplantationHumansLongitudinal StudiesQuality of LifeTransplant RecipientsDialysisGastrointestinal symptomsHIVKidney transplant

Identifiers

PMID34156597
OpenAlexW3173963680

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.