ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2022
Assessing forgetfulness and polypharmacy and their impact on health-related quality of life among patients with hypertension and dyslipidemia in Greece during the COVID-19 pandemic.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 19 citations in OpenAlex.
- Medication literacy among community-dwelling older adults in Shenzhen: a 2024 cross-sectional survey with psychometric evidence.Frontiers in public health · 2026Article
- Forgetfulness to Take Antihypertensive Medications and Poor Blood Pressure Control in Older Adults With Type 2 Diabetes and Hypertension in Vietnam.Journal of clinical hypertension (Greenwich, Conn.) · 2025Observational
- Acceptance of Illness and Health-Related Quality of Life in Patients After Myocardial Infarction-Narrative Review.Journal of clinical medicine · 2025Review
- Medication adherence and quality of life among geriatric patients: Insights from a hospital-based cross-sectional study in India.PloS one · 2024Article
- Association between medication adherence and health-related quality of life of patients with hypertension and dyslipidemia.Hormones (Athens, Greece) · 2023Article
- Assessing a Pharmacist-Enabled Intervention to Improve Adherence to Medication for Hypertension, Dyslipidemia, and Chronic Venous Circulation Disorders in Greece.Patient preference and adherence · 2023Article
- Association between medication adherence and health-related quality of life of patients with diabetes.Hormones (Athens, Greece) · 2022Article
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Authors and funding
4 authors at 4 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
purposeWe estimate the association between forgetfulness to take medications as prescribed and polypharmacy and health-related quality of life (HRQoL) among a cohort of patients with hypertension, dyslipidemia or both in Greece during the COVID-19 pandemic.
methodsA telephone survey of 1018 randomly selected adults was conducted in Greece in June 2020. Participants were included in the survey, if they (a) had a diagnosis of hypertension, dyslipidemia or both and (b) were on prescription treatment for these conditions. HRQoL was calculated using the short form (SF) -12 Patient Questionnaire. A multivariable generalized linear regression model (GLM) was used to estimate the association between forgetfulness and polypharmacy and HRQoL, controlling for sociodemographic and health-related covariates.
resultsOverall, 351 respondents met the inclusion criteria, of whom 28 did not fully complete the questionnaire (response rate: 92%, n = 323). Of those, 37% were diagnosed with hypertension only, 28% with dyslipidemia only, and 35% with both. Most reported good to average physical (64.1%) and mental health (48.6%). Overall, 25% indicated that they sometimes forget to take their prescribed medications, and 12% took two or more pills multiple times daily. Total HRQoL score was 68.9% (s.d. = 18.0%). About 10% of participants reported paying less attention to their healthcare condition during the pandemic. Estimates of multivariable analyses indicated a negative association between forgetfulness (- 9%, adjusted β: - 0.047, 95% confidence interval - 0.089 to - 0.005, p = 0.029), taking two or more pills multiple times daily compared to one pill once a day (- 16%, adjusted β: - 0.068, 95% confidence interval - 0.129 to - 0.008, p = 0.028) and total HRQoL.
conclusionOur results suggest that among adult patients with hypertension, dyslipidemia or both in Greece, those who forget to take their medications and those with more complex treatment regimens had lower HRQoL. Such patients merit special attention and require targeted approaches by healthcare providers to improve treatment compliance and health outcomes.
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