Evidence map›Paper›PMID 34156592›Full record

ArticleLa Radiologia medica2021

Prediction of placenta accreta spectrum in patients with placenta previa using clinical risk factors, ultrasound and magnetic resonance imaging findings.

Valeria Romeo, Francesco Verde, Laura Sarno, Sonia Migliorini, Mario Petretta, Pier Paolo Mainenti, Maria D'Armiento, Maurizio Guida, Arturo Brunetti, Simone Maurea

Registry-linked trialAbstract read
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In one paragraph

Article in La Radiologia medica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06219564 (Diagnostic Accuracy of MRI to Predict Peripartum Hysterectomy and Neonatal Mortality in Total Placenta Previa), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06219564 nacompletednot on this map

Diagnostic Accuracy of MRI to Predict Peripartum Hysterectomy and Neonatal Mortality in Total Placenta Previa: A Retrospective Cohort Study.

TypeinterventionalSponsorSaglik Bilimleri Universitesi Gazi Yasargil Training and Research HospitalRan2017 to 2023Enrolled277ConditionsMaternal, ProcedureArmsPeripartum total abdominal hysterectomy (p-TAH), Cesarean Section (C/S), Neonatal mortality
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Valeria RomeoDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Via S. Pansini, 5, 80123, Naples, Italy.
Francesco VerdeDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Via S. Pansini, 5, 80123, Naples, Italy. francescoverde87@gmail.com.ORCID http://orcid.org/0000-0002-9823-4678
Laura SarnoDepartment of Neuroscience, Reproductive and Dentistry Sciences, University of Naples "Federico II", Naples, Italy.
Sonia MiglioriniDepartment of Neuroscience, Reproductive and Dentistry Sciences, University of Naples "Federico II", Naples, Italy.
Mario PetrettaDepartment of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
Pier Paolo MainentiInstitute of Biostructures and Bioimaging of the National Council of Research (CNR), Naples, Italy.
Maria D'ArmientoDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Via S. Pansini, 5, 80123, Naples, Italy.
Maurizio GuidaDepartment of Neuroscience, Reproductive and Dentistry Sciences, University of Naples "Federico II", Naples, Italy.
Arturo BrunettiDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Via S. Pansini, 5, 80123, Naples, Italy.
Simone MaureaDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Via S. Pansini, 5, 80123, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo predict placental accreta spectrum (PAS) in patients with placenta previa (PP) evaluating clinical risk factors (CRF), ultrasound (US) and magnetic resonance imaging (MRI) findings.

methodsSeventy patients with PP were retrospectively selected. CRF were retrieved from medical records. US and MRI images were evaluated to detect imaging signs suggestive of PAS. Univariable analysis was performed to identify CRF, US and MRI signs associated with PAS considering histology as standard of reference. Receiver operating characteristic curve (ROC) analysis was performed, and the area under the curve (AUC) was calculated. Multivariable analysis was also performed.

resultsAt univariable analysis, the number of previous cesarean section, smoking, loss of the retroplacental clear space, myometrial thinning < 1 mm, placental lacunae, intraplacental dark bands (IDB), focal interruption of myometrial border (FIMB) and abnormal vascularity were statistically significant. The AUC in predicting PAS progressively increased using CRF, US and MRI signs (0.69, 0.79 and 0.94, respectively; p < 0.05); the accuracy of MRI alone was similar to that obtained combining CRF, US and MRI variables (AUC = 0.97) and was significantly higher (p < 0.05) than that combining CRF and US (AUC = 0.83). Multivariable analysis showed that only IDB (p = 0.012) and FIMB (p = 0.029) were independently associated with PAS.

conclusionsMRI is the best modality to predict PAS in patients with PP independently from CRF and/or US finding. It is reasonable to propose the combined assessment of CRF and US as the first diagnostic level to predict PAS, sparing MRI for selected cases in which US findings are uncertain for PAS.

Indexed as

Magnetic Resonance ImagingPlacenta AccretaUltrasonography, PrenatalAdultAnalysis of VarianceArea Under CurveFemaleHumansMiddle AgedPlacenta PreviaPregnancyRetrospective StudiesRisk FactorsROC CurveClinical risk factorsMagnetic resonance imagingPlacental accreta spectrumPlacenta previaUltrasound

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.