Evidence map›Paper›PMID 34156543›Full record

ArticleCurrent microbiology2021

Antimicrobial Activity and Functional Genes of Actinobacteria from Coastal Wetland.

Lei Chen, Ziwei Wang, Shuang Du, Guangyu Wang

Abstract read
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In one paragraph

Article in Current microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. International journal of systematic and evolutionary microbiology · 2024
    Article
  2. Article
  3. GenusMarine drugs · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lei ChenDepartment of Bioengineering, School of Marine Science and Technology, Harbin Institute of Technology, Weihai, 264209, China.
Ziwei WangDepartment of Bioengineering, School of Marine Science and Technology, Harbin Institute of Technology, Weihai, 264209, China.
Shuang DuDepartment of Bioengineering, School of Marine Science and Technology, Harbin Institute of Technology, Weihai, 264209, China.
Guangyu WangDepartment of Bioengineering, School of Marine Science and Technology, Harbin Institute of Technology, Weihai, 264209, China. wanggy18_2007@163.com.ORCID http://orcid.org/0000-0001-8247-8419

Funding

Discipline Construction Guide Foundation in Harbin Institute of Technology at Weihai WH20150204Discipline Construction Guide Foundation in Harbin Institute of Technology at Weihai WH20160205Research Innovation Foundation in Research Innovation Foundation in Harbin Institute of Technology at Weihai 2019KYCXJJYB15
6 · The paper itself

Abstract

Isolation of culturable actinobacteria from coastal wetlands and screening of their potential biological activities are important for the development of new marine natural products. We collected and isolated 109 actinobacteria from the Sanggou Bay and the Swan Lake wetlands, in the coast of Weihai, China. Of the 109 isolates, 104 had antimicrobial activity against at least one indicator strain. The 35 strains with the strongest inhibitory effects were chosen for the screening of the biosynthesis gene clusters of polyketide synthase (PKS) and non-ribosomal peptide synthetase (NRPS). Four strains with the PKS gene, six strains with the NRPS gene, and three strains with both genes were detected. Eight of the 13 strains with PKS or NRPS genes belong to the genera Streptomyces, and other strains belonged to genus Micromonospora, Nocardiopsis, Rhodococcus, Saccharomonospora, and Staphylococcus. Our results reveal that the culturable actinobacteria isolated from coastal wetlands showed broad-spectrum antimicrobial activities, and some strains with antimicrobial activities possessed PKS and NRPS genes. Thus, culturable actinobacteria from coastal wetlands may contain potential new bioactive substances.

Indexed as

ActinobacteriaAnti-Infective AgentsChinaPhylogenyRNA, Ribosomal, 16SWetlandsAnti-Infective AgentsRNA, Ribosomal, 16S

Identifiers

PMID34156543

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.