Evidence map›Paper›PMID 34156463›Full record

ArticleThe Journal of clinical endocrinology and metabolism2021

Academic Performance in Adolescents Born to Mothers With Gestational Diabetes-A National Danish Cohort Study.

Gerda Ferja Heldarskard, Anne Lærke Spangmose, Anna-Karina Aaris Henningsen, Rikke Wiingreen, Erik Lykke Mortensen, Tina Wullum Gundersen, Rikke Beck Jensen, Sine Knorr, Peter Damm, Julie Lyng Forman and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Neurodevelopmental outcomes of infants of diabetic mothers.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Gerda Ferja HeldarskardThe Fertility Clinic, Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0001-8650-9227
Anne Lærke SpangmoseThe Fertility Clinic, Rigshospitalet, Copenhagen, Denmark.
Anna-Karina Aaris HenningsenThe Fertility Clinic, Rigshospitalet, Copenhagen, Denmark.
Rikke WiingreenUniversity of Copenhagen, Copenhagen, Denmark.
Erik Lykke MortensenUniversity of Copenhagen, Copenhagen, Denmark.
Tina Wullum GundersenDepartment of Gynecology and Obstetrics, Nordsjællands Hospital, Hillerød, Denmark.
Rikke Beck JensenUniversity of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-4522-672X
Sine KnorrSteno Diabetes Center Aarhus, Aarhus University Hospital, Denmark.
Peter DammUniversity of Copenhagen, Copenhagen, Denmark.
Julie Lyng FormanSection of Biostatistics, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Anja PinborgThe Fertility Clinic, Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0002-8340-104X
Tine Dalsgaard ClausenDepartment of Gynecology and Obstetrics, Nordsjællands Hospital, Hillerød, Denmark.
University of Copenhagen · DKSteno Diabetes Centers · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextThe prevalence of gestational diabetes mellitus (GDM) is increasing, and intrauterine hyperglycemia is suspected to affect offspring cognitive function.

objectiveWe assessed academic performance by grade point average (GPA) in children aged 15 to 16 years at compulsory school graduation, comparing offspring exposed to GDM (O-GDM) with offspring from the background population (O-BP).

methodsThis register-based, cohort study comprised all singletons born in Denmark between 1994 and 2001 (O-GDM: n = 4286; O-BP: n = 501 045). Standardized and internationally comparable GPAs were compared in univariate and multivariable linear models. Main outcome measures included the adjusted mean difference in GPA. We also analyzed the probability of having a high GPA, a GPA below passing, and no GPA registered.

resultsO-GDM had a GPA of 6.29 (SD 2.52), whereas O-BP had a GPA of 6.78 (SD 2.50). The adjusted mean difference was -0.36 (95% CI, -0.44 to -0.29), corresponding to a Cohen's D of 0.14. O-GDM had a lower probability of obtaining a high GPA (adjusted odds ratio [aOR] 0.68; 95% CI, 0.59 to 0.79), while their risk of obtaining a GPA below passing was similar to O-BP (aOR 1.20; 95% CI, 0.96 to 1.50). O-GDM had a higher risk of not having a GPA registered (aOR 1.38; 95% CI, 1.24 to 1.53).

conclusionAcademic performance in O-GDM was marginally lower than in O-BP. However, this difference is unlikely to be of clinical importance.

Indexed as

Academic PerformanceAdolescentAdultCohort StudiesDenmarkDiabetes, GestationalFemaleFollow-Up StudiesHumansMaleMothersPregnancyPrenatal Exposure Delayed EffectsPrognosisRegistriesacademic performancecognitive developmentdiabetes in pregnancygestational diabetes mellituslong-term outcomes in offspring

Identifiers

PMID34156463
PMCPMC8530709
OpenAlexW3173776633

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.