Evidence map›Paper›PMID 34156172›Full record

ArticleZoological research2021

Genomes reveal selective sweeps in kiang and donkey for high-altitude adaptation.

Lin Zeng, He-Qun Liu, Xiao-Long Tu, Chang-Mian Ji, Xiao Gou, Ali Esmailizadeh, Sheng Wang, Ming-Shan Wang, Ming-Cheng Wang, Xiao-Long Li and 16 more

Open access · diamondAbstract read
In one paragraph

Article in Zoological research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  14. Tibetan wild ass,Journal of equine science · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 10 institutions in 7 countries.

Lin ZengState Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.
He-Qun LiuState Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.
Xiao-Long TuAnnoroad Gene Tech. (Beijing) Co., Ltd., Beijing 100176, China.
Chang-Mian JiHainan Key Laboratory for Biosafety Monitoring and Molecular Breeding in Off-Season Reproduction Regions, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan 571101, China.
Xiao GouCollege of Animal Science and Technology, Yunnan Agricultural University, Kunming, Yunnan 650201, China.
Ali EsmailizadehDepartment of Animal Science, Faculty of Agriculture, Shahid Bahonar University of Kerman, Kerman, PB 76169-133, Iran.
Sheng WangState Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.
Ming-Shan WangState Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.
Ming-Cheng WangBiomarker Technologies Corporation, Beijing 101300, China.
Xiao-Long LiBiomarker Technologies Corporation, Beijing 101300, China.
Hadi CharatiState Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.
Adeniyi C AdeolaState Key Laboratory of Genetic Resources and Evolution, Yunnan Laboratory of Molecular Biology of Domestic Animals, Germplasm Bank of Wild Species, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.
Rahamon Akinyele Moshood AdedokunDepartment of Veterinary Medicine, University of Ibadan, Ibadan 200284, Nigeria.
Olatunbosun OladipoFederal College of Animal Health and Production Technology, Moor-Plantation, Ibadan, Nigeria.
Sunday Charles OlaogunDepartment of Veterinary Medicine, University of Ibadan, Ibadan 200284, Nigeria.
Oscar J SankeTaraba State Ministry of Agriculture and Natural Resources, Jalingo 660221, Nigeria.
Mangbon Godwin FDivision of Veterinary Office, Serti 663101, Nigeria.
Sheila Cecily OmmehInstitute For Biotechnology Research Jomo Kenyatta University of Agriculture and Technology, Nairobi 62000-00200, Kenya.
Bernard AgwandaDepartment of Zoology, National Museums of Kenya, Nairobi 40658-00100, Kenya.
Jacqueline Kasiiti LichotiState Department of Livestock, Ministry of Agriculture, Livestock, Fisheries and Irrigation, Nairobi, Kenya.
Jian-Lin HanCAAS-ILRI Joint Laboratory on Livestock and Forage Genetic Resources, Institute of Animal Science, Chinese Academy of Agricultural Sciences (CAAS), Beijing 100193, China.
Hong-Kun ZhengBiomarker Technologies Corporation, Beijing 101300, China.
Chang-Fa WangEquus Laboratory, Dairy Cattle Research Center, Shandong Academy of Agricultural Sciences, Ji'nan, Shandong 250131, China.
Ya-Ping ZhangState Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.
Laurent A F FrantzSchool of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London E1 4NS, UK. E-mail:laurent.frantz@qmul.ac.uk.
Dong-Dong WuState Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.
Kunming Institute of Zoology · CNUniversity of Ibadan · NGBiomarker Technologies (China) · CNChinese Academy of Tropical Agricultural Sciences · CNJomo Kenyatta University of Agriculture and Technology · KEMinistry of Agriculture Livestock and Fisheries · KEQueen Mary University of London · GBShahid Bahonar University of Kerman · IRAlbert Einstein College of Medicine · USTaraba State University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last several hundred years, donkeys have adapted to high-altitude conditions on the Tibetan Plateau. Interestingly, the kiang, a closely related equid species, also inhabits this region. Previous reports have demonstrated the importance of specific genes and adaptive introgression in divergent lineages for adaptation to hypoxic conditions on the Tibetan Plateau. Here, we assessed whether donkeys and kiangs adapted to the Tibetan Plateau via the same or different biological pathways and whether adaptive introgression has occurred. We assembled a

Indexed as

AltitudeGenomeAdaptation, PhysiologicalAnimalsBasic Helix-Loop-Helix ProteinsBiological EvolutionEndothelial PAS Domain-Containing Protein 1EquidaeGene Expression ProfilingGene Expression RegulationSpecies SpecificityBasic Helix-Loop-Helix ProteinsEndothelial PAS Domain-Containing Protein 1AdaptationDonkeyHigh altitudeKiangSelection

Identifiers

PMID34156172
PMCPMC8317180
OpenAlexW3174717593

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.