Evidence map›Paper›PMID 34155902›Full record

ArticleJournal of the American Heart Association2021

Sex Differences in Prehospital Delays in Patients With ST-Segment-Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention.

Julia Stehli, Diem Dinh, Misha Dagan, Stephen J Duffy, Angela Brennan, Karen Smith, Emily Andrew, Ziad Nehme, Christopher M Reid, Jeffrey Lefkovits and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
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  3. Observational
  4. Review
  5. Article
  6. Article
  7. Redesigning medicine: integrating sex and gender for better health outcomes.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
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  16. Review
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  18. Article
  19. Factors Influencing Time to First Medical Contact in Patients with Acute ST-Segment Elevation Myocardial Infarction: A Retrospective Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Julia StehliSchool of Clinical Sciences at Monash Health Monash Cardiovascular Research Centre Monash University Melbourne Australia.
Diem DinhCentre of Cardiovascular Research and Education in Therapeutics School of Public Health and Preventive Medicine Monash University Melbourne Australia.
Misha DaganDepartment of General Medicine The Alfred Hospital Melbourne Australia.
Stephen J DuffyCentre of Cardiovascular Research and Education in Therapeutics School of Public Health and Preventive Medicine Monash University Melbourne Australia.
Angela BrennanCentre of Cardiovascular Research and Education in Therapeutics School of Public Health and Preventive Medicine Monash University Melbourne Australia.
Karen SmithCentre for Research and Evaluation Ambulance Victoria Melbourne Australia.
Emily AndrewCentre for Research and Evaluation Ambulance Victoria Melbourne Australia.
Ziad NehmeCentre for Research and Evaluation Ambulance Victoria Melbourne Australia.
Christopher M ReidCentre for Research and Evaluation Ambulance Victoria Melbourne Australia.
Jeffrey LefkovitsCentre of Cardiovascular Research and Education in Therapeutics School of Public Health and Preventive Medicine Monash University Melbourne Australia.
Dion StubCentre of Cardiovascular Research and Education in Therapeutics School of Public Health and Preventive Medicine Monash University Melbourne Australia.
Sarah ZamanSchool of Clinical Sciences at Monash Health Monash Cardiovascular Research Centre Monash University Melbourne Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Women with ST-segment-elevation myocardial infarction experience delays in reperfusion compared with men with little data on each time component from symptom onset to reperfusion. This study analyzed sex discrepancies in patient delays, prehospital system delays, and hospital delays. Methods and Results Consecutive patients with ST-segment-elevation myocardial infarction treated with percutaneous coronary intervention across 30 hospitals in the Victorian Cardiac Outcomes Registry (2013-2018) were analyzed. Data from the Ambulance Victoria Data warehouse were used to perform linkage to the Victorian Cardiac Outcomes Registry for all patients transported via emergency medical services (EMS). The primary end point was EMS call-to-door time (prehospital system delay). Secondary end points included symptom-to-EMS call time (patient delay), door-to-device time (hospital delay), 30-day mortality, major adverse cardiovascular events, and major bleeding. End points were analyzed according to sex and adjusted for age, comorbidities, cardiogenic shock, cardiac arrest, and symptom onset time. A total of 6330 (21% women) patients with ST-segment-elevation myocardial infarction were transported by EMS. Compared with men, women had longer adjusted geometric mean symptom-to-EMS call times (47.0 versus 44.0 minutes;

Indexed as

Percutaneous Coronary InterventionSex CharacteristicsTime-to-TreatmentAgedAged, 80 and overAustraliaEmergency Medical ServicesFemaleHospital MortalityHumansLogistic ModelsMaleMiddle AgedRegistriesRisk FactorsST Elevation Myocardial Infarctionfirst medical contactischemic timeprehospital delaysex discrepanciesST‐segment–elevation myocardial infarction

Identifiers

PMID34155902
PMCPMC8403281

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.