ArticleInternational journal of fertility & sterility2021
Follicular Fluid Zinc Level and Oocyte Maturity and Embryo Quality in Women with Polycystic Ovary Syndrome.
Article in International journal of fertility & sterility, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05393011 (Vitamin D and Some Antioxidants and Trace Elements Levels in Women), which is not on this map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Vitamin D and Some Antioxidants and Trace Elements Levels in Women: Relationship With I.V.F Outcomes
Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Ovovid trial: the effect of a probiotic micronutrients supplement on oocyte retrieval and quality in oocyte donors. A double blind, randomized controlled trial.Journal of assisted reproduction and genetics · 2026Trial
- Assessment and prediction models for the quantitative and qualitative reserve of the ovary using machine learning.Journal of ovarian research · 2025Article
- Evaluation of the follicular fluid thiol/disulfide balance among patients with poor ovarian response.Clinical and experimental reproductive medicine · 2025Article
- The interplay between oxidative stress, zinc, and metabolic dysfunction in polycystic ovarian syndrome.Molecular and cellular biochemistry · 2025Review
- Zinc deficiency deteriorates ovarian follicle development and function by inhibiting mitochondrial function.Journal of ovarian research · 2024Article
- The Role of One-Carbon Metabolism and Methyl Donors in Medically Assisted Reproduction: A Narrative Review of the Literature.International journal of molecular sciences · 2024Review
- ZnT 9 Involvement in Estradiol-Modulated Zinc Homeostasis of the Human Follicular Microenvironment.Biological trace element research · 2024Article
- Review
- The prospect of artificial intelligence to personalize assisted reproductive technology.NPJ digital medicine · 2024Review
- Methods for Assessing Oocyte Quality: A Review of Literature.Biomedicines · 2022Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPolycystic ovary syndrome (PCOS) is considered to be one of the most common endocrine disorders in women of reproductive age. Zinc, a vital trace element in the body, plays a key role in maintaining health, especially due to its antioxidant role. On the other hand, lack of antioxidants and oxidative stress can adversely affect oocytes quality and consequently fertility rate. The available studiesthat report the effect of follicular fluid (FF) zinc in terms of the number and quality of the oocytes in infertile women with PCOS, are few and not consistent. We decided to investigate this issue. MATERIALS AND
methodsIn this cross-sectional study, from the women with PCOS referring to Omolbanin Hospital, Dezful, Iran (February to December 2019), a total of 90 samples (follicular fluid, oocytes, and embryos) were collected from those who had undergone
resultsThe amount of FF zinc was not associated with any significant differences in the number of oocytes and metaphase I (MI) and germinal vesicle (GV) oocytes, but a significant decrease was observed in the number of metaphase II (MII) oocytes at zinc values lessthan 35 μg/dL. The FF zinc levels lessthan 35 μg/dL were also significantly associated with decreased embryo quality.
conclusionA significant relationship was found between the level of FF zinc and the quality and the number of oocytes taken from the ovaries of infertile patients with PCOS history who were candidates for IVF treatment as well as the number of high quality embryos.
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