ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021
Infrared Plasmonic Biosensor with Tetrahedral DNA Nanostructure as Carriers for Label-Free and Ultrasensitive Detection of miR-155.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 93 citations in OpenAlex.
- AI‑driven photonic noses: from conventional sensors to cloud‑to-edge intelligent microsystems.Microsystems & nanoengineering · 2025Review
- Mass-Manufactured Gradient Plasmonic Metasurfaces for Enhanced Mid-IR Spectrochemical Analysis of Complex Biofluids.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Surface-enhanced spectroscopy technology based on metamaterials.Microsystems & nanoengineering · 2025Review
- Advancements in functional tetrahedral DNA nanostructures for multi-biomarker biosensing: Applications in disease diagnosis, food safety, and environmental monitoring.Materials today. Bio · 2025Review
- Advances in MEMS, Optical MEMS, and Nanophotonics Technologies for Volatile Organic Compound Detection and Applications.Small science · 2025Review
- Plasmonic Biosensors in Cancer-Associated miRNA Detection.Biosensors · 2025Review
- Breast Tumor Diagnosis Based on Molecular Learning Vector Quantization Neural Networks.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Detecting mir-155-3p through a Molecular Beacon Bead-Based Assay.Molecules (Basel, Switzerland) · 2024Article
- Surface plasmons-phonons for mid-infrared hyperspectral imaging.Science advances · 2024Article
- Multiarmed DNA jumper and metal-organic frameworks-functionalized paper-based bioplatform for small extracellular vesicle-derived miRNAs assay.Journal of nanobiotechnology · 2024Article
- Long-term monitoring of ultratrace nucleic acids using tetrahedral nanostructure-based NgAgo on wearable microneedles.Nature communications · 2024Article
- Advances and Applications of Metal-Organic Frameworks (MOFs) in Emerging Technologies: A Comprehensive Review.Global challenges (Hoboken, NJ) · 2024Review
- Dynamic construction of refractive index-dependent vibrations using surface plasmon-phonon polaritons.Nature communications · 2023Article
- Mid-infrared integrated electro-optic modulators: a review.Nanophotonics (Berlin, Germany) · 2023Review
- Research Progress in Surface-Enhanced Infrared Absorption Spectroscopy: From Performance Optimization, Sensing Applications, to System Integration.Nanomaterials (Basel, Switzerland) · 2023Review
- Artificial intelligence enhanced sensors - enabling technologies to next-generation healthcare and biomedical platform.Bioelectronic medicine · 2023Review
- Dielectric Cavity-Insulator-Metal (DCIM) Metamaterial Absorber in Visible Range.Nanomaterials (Basel, Switzerland) · 2023Article
- Machine learning-augmented surface-enhanced spectroscopy toward next-generation molecular diagnostics.Nanoscale advances · 2023Review
- Advances in regenerative medicine applications of tetrahedral framework nucleic acid-based nanomaterials: an expert consensus recommendation.International journal of oral science · 2022Review
- MOF/Polymer-Integrated Multi-Hotspot Mid-Infrared Nanoantennas for Sensitive Detection of CONano-micro letters · 2022Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
MicroRNAs play an important role in early development, cell proliferation, apoptosis, and cell death, and are aberrantly expressed in many types of cancers. To understand their function and diagnose cancer at an early stage, it is crucial to quantitatively detect microRNA without invasive labels. Here, a plasmonic biosensor based on surface-enhanced infrared absorption (SEIRA) for rapid, label-free, and ultrasensitive detection of miR-155 is reported. This technology leverages metamaterial perfect absorbers stimulating the SEIRA effect to provide up to 1000-fold near-field intensity enhancement over the microRNA fingerprint spectral bands. Additionally, it is discovered that the limit of detection (LOD) of the biosensor can be greatly improved by using tetrahedral DNA nanostructure (TDN) as carriers. By using near-field enhancement of SEIRA and specific binding of TDN, the biosensor achieves label-free detection of miR-155 with a high sensitivity of 1.162% pm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.