Evidence map›Paper›PMID 34155560›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2021

Gonioscopy-assisted transluminal trabeculotomy in primary angle-closure glaucoma.

Eamon Sharkawi, Paul H Artes, Daniel Josef Lindegger, Maria Laura Dari, Mohamad El Wardani, Jérôme Pasquier, Adriano Guarnieri

Abstract read
PubMed Publisher
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Ab Interno Goniotomy/Goniectomy TechniquesTurkish journal of ophthalmology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Is GATT the Answer?Journal of current glaucoma practice
    Article
  19. Contemporary Approach to Narrow Angles.Journal of ophthalmic & vision research
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Eamon SharkawiSwiss Eye Centre, Avenue de Rumine 64, Lausanne, 1005, Switzerland. e.sharkawi@swisseyecentre.ch.
Paul H ArtesUniversity of Plymouth, Plymouth, UK.
Daniel Josef LindeggerJules Gonin Eye Hospital, Lausanne, Switzerland.
Maria Laura DariSwiss Eye Centre, Avenue de Rumine 64, Lausanne, 1005, Switzerland.
Mohamad El WardaniMoorfields Eye Hospital, London, UK.
Jérôme PasquierCenter for Primary Care and Public Health, Unisanté, University of Lausanne, Lausanne, Switzerland.
Adriano GuarnieriSwiss Eye Centre, Avenue de Rumine 64, Lausanne, 1005, Switzerland.
Centre universitaire de médecine générale et santé publique, Lausanne · CHHôpital Ophtalmique Jules-Gonin · CHUniversity College London · GBUniversity of Plymouth · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to report on outcomes of gonioscopy-assisted transluminal trabeculotomy (GATT) in eyes with primary angle-closure glaucoma (PACG).

methodsThis study is a prospective, interventional, non-comparative case series. A total of 103 eyes from 88 patients with PACG underwent an ab interno trabeculotomy, using either a 5.0 polypropylene suture or an illuminated microcatheter, with up to 24 months of follow-up. The main outcome measures were intraocular pressure (IOP), number of antiglaucoma medications, success rate (IOP reduction ≥ 20% from baseline or IOP between 6 and 21 mmHg, without further glaucoma surgery) and complication rate.

resultsThe mean preoperative IOP was 21.4 (SD 7.4) mmHg using 2.5 (SD 1.1) glaucoma medications. These decreased postoperatively to 12.1 (SD 2.4) mmHg and 0.8 (SD 1.2) medications, at 24 months (P < 0.05). Success rate was 78% at 24 months of follow-up, and complication rate was 4.8%.

conclusionAt 24 months of follow-up, our results for GATT in PACG demonstrate that this procedure effectively lowers IOP in this subtype of glaucoma, with a low complication rate.

Indexed as

Glaucoma, Angle-ClosureGlaucoma, Open-AngleTrabeculectomyFollow-Up StudiesGonioscopyHumansIntraocular PressureProspective StudiesRetrospective StudiesTreatment OutcomeAngle closureGATTGonioscopy-assisted transluminal trabeculotomyMIGSMinimally invasive glaucoma surgery

Identifiers

PMID34155560
OpenAlexW3173720724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.