ArticleEndocrine2021
The association between vitamin D3 and diabetes in both hyperuricemia and non-hyperuricemia populations.
Article in Endocrine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 20 citations in OpenAlex.
- Dietary magnesium intake modified association between visceral adiposity index and chronic kidney disease: a cross-sectional study.Food & nutrition research · 2026Article
- Bibliometric and visual assessment of research trends in the management of hyperuricemia (HUA).Clinical rheumatology · 2025Article
- Nonlinear relationship between oxidative balance score and hyperuricemia: analyses of NHANES 2007-2018.Nutrition journal · 2024Article
- A study on the correlation between hyperuricemia and TG/HDL-c ratio in the Naxi ethnic group at high-altitude regions of Yunnan.Frontiers in medicine · 2024Article
- The Heterogeneity of Symptom Burden and Fear of Progression Among Kidney Transplant Recipients: A Latent Class Analysis.Psychology research and behavior management · 2024Article
- The prevalence of hyperuricemia and its correlates in Zhuang nationality, Nanning, Guangxi Province.Journal of clinical laboratory analysis · 2022Article
- Association between vitamin D3 levels and insulin resistance: a large sample cross-sectional study.Scientific reports · 2022Article
- Dietary Magnesium Intake Level Modifies the Association Between Vitamin D and Insulin Resistance: A Large Cross-Sectional Analysis of American Adults.Frontiers in nutrition · 2022Article
- Association Between Globulin and Diabetic Nephropathy in Type2 Diabetes Mellitus Patients: A Cross-Sectional Study.Frontiers in endocrinology · 2022Article
- Association Between Visceral Adiposity Index and Insulin Resistance: A Cross-Sectional Study Based on US Adults.Frontiers in endocrinology · 2022Article
- Dietary Magnesium Intake Affects the Vitamin D Effects on HOMA-β and Risk of Pancreatic β-Cell Dysfunction: A Cross-Sectional Study.Frontiers in nutrition · 2022Article
- Serum 25(OH)D Levels Modify the Association between Triglyceride and IR: A Cross-Sectional Study.International journal of endocrinology · 2022Article
- Associations between TG/HDL ratio and insulin resistance in the US population: a cross-sectional study.Endocrine connections · 2021Article
- Associations of Triglycerides/High-Density Lipoprotein Cholesterol Ratio With Insulin Resistance, Impaired Glucose Tolerance, and Diabetes in American Adults at Different Vitamin D3 Levels.Frontiers in endocrinology · 2021Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies have shown that hyperuricemia is involved in diabetes, obesity, hypertension, chronic kidney disease, and other diseases. At the same time, studies have shown that vitamin D3 levels in the body are linked to the onset of diabetes. However, there is currently no sufficient evidence to prove whether this connection is affected by the uric acid level. Therefore, we attempted to investigate the association between vitamin D3 content and the occurrence of diabetes in populations with different uric acid levels though the data of NHANES database from 2009 to 2018.
methodUsing the NHANES database, we performed a cross-sectional analysis. The participants were chosen based on stringent inclusion and exclusion requirements. This study finally included a total number of 16,735 individuals. Multivariate logistic regression analysis was used to investigate the association between vitamin D3 and diabetes mellitus in hyperuricemia and non-hyperuricemia patients after complete adjustment, and multivariate linear regression analysis was used to illustrate the association between vitamin D3 and uric acid.
resultThe results showed that the association between vitamin D3 and diabetes was weakened in hyperuricemia patients (OR 0.95 (0.92,0.98)). An independent association was discovered between vitamin D3 and uric acid (β -0.12 (-0.16, -0.07)) in all groups of population.
conclusionsThis study shows that vitamin D3 content is associated with the incidence of diabetes in people with high level of uric acid. This study offers a fresh perspective on the elements that influence the etiology of diabetes in hyperuricemia patients.
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