Evidence map›Paper›PMID 34155450›Full record

ArticleBiomedical reports2021

Insulin-like growth factor-I and wound healing, a potential answer to non-healing wounds: A systematic review of the literature and future perspectives.

Zoe Garoufalia, Argyro Papadopetraki, Elli Karatza, Dimitrios Vardakostas, Anastassios Philippou, Gregory Kouraklis, Dimitrios Mantas

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zoe GaroufaliaSecond Department of Propaedeutic Surgery, Laiko General Hospital, Athens 11527, Greece.
Argyro PapadopetrakiDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece.
Elli KaratzaSecond Department of Propaedeutic Surgery, Laiko General Hospital, Athens 11527, Greece.
Dimitrios VardakostasSecond Department of Propaedeutic Surgery, Laiko General Hospital, Athens 11527, Greece.
Anastassios PhilippouDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece.
Gregory KouraklisSecond Department of Propaedeutic Surgery, Laiko General Hospital, Athens 11527, Greece.
Dimitrios MantasSecond Department of Propaedeutic Surgery, Laiko General Hospital, Athens 11527, Greece.
Laiko General Hospital of Athens · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The induction of wound healing by insulin-like growth factor-I (IGF-I) has been demonstrated in several animal studies; however, there are disproportionately fewer studies assessing its value in humans. The aim of the present review is to provide a comprehensive summary of all the available evidence pertaining to the effects of IGF-I administration on the process of wound anaplasias, both in human tissues

Indexed as

anaplasiaschronic ulcersIGF-Itissue regeneration

Identifiers

PMID34155450
PMCPMC8212444
OpenAlexW3166799293

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.