ArticleCommunications biology2021
Guard cells control hypocotyl elongation through HXK1, HY5, and PIF4.
Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Responses of Male and Female Cucumber Flowers toPlants (Basel, Switzerland) · 2026Article
- Hexokinase 1 facilitates post-germinative seedling growth through its catalytic function.The Plant journal : for cell and molecular biology · 2026Article
- Natural variation links seedling hypocotyl growth with water loss in Arabidopsis.The Plant journal : for cell and molecular biology · 2026Article
- Decoding the sugar-strigolactone crosstalk: new frontier in plant growth and stress resilience.Horticulture research · 2026Article
- Soybean hypocotyl elongation is regulated by a MYB33-SWEET11/21-GA2ox8c module involving long-distance sucrose transport.Plant biotechnology journal · 2024Article
- The role of light in regulating plant growth, development and sugar metabolism: a review.Frontiers in plant science · 2024Review
- Growing at the right time: interconnecting the TOR pathway with photoperiod and circadian regulation.Journal of experimental botany · 2022Article
- Effect of Light Quality on Metabolomic, Ionomic, and Transcriptomic Profiles in Tomato Fruit.International journal of molecular sciences · 2022Article
- SoybeanFrontiers in plant science · 2021Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The hypocotyls of germinating seedlings elongate in a search for light to enable autotrophic sugar production. Upon exposure to light, photoreceptors that are activated by blue and red light halt elongation by preventing the degradation of the hypocotyl-elongation inhibitor HY5 and by inhibiting the activity of the elongation-promoting transcription factors PIFs. The question of how sugar affects hypocotyl elongation and which cell types stimulate and stop that elongation remains unresolved. We found that overexpression of a sugar sensor, Arabidopsis hexokinase 1 (HXK1), in guard cells promotes hypocotyl elongation under white and blue light through PIF4. Furthermore, expression of PIF4 in guard cells is sufficient to promote hypocotyl elongation in the light, while expression of HY5 in guard cells is sufficient to inhibit the elongation of the hy5 mutant and the elongation stimulated by HXK1. HY5 exits the guard cells and inhibits hypocotyl elongation, but is degraded in the dark. We also show that the inhibition of hypocotyl elongation by guard cells' HY5 involves auto-activation of HY5 expression in other tissues. It appears that guard cells are capable of coordinating hypocotyl elongation and that sugar and HXK1 have the opposite effect of light on hypocotyl elongation, converging at PIF4.
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