Evidence map›Paper›PMID 34155265›Full record

ArticleScientific reports2021

MRI-derived radiomics model for baseline prediction of prostate cancer progression on active surveillance.

Nikita Sushentsev, Leonardo Rundo, Oleg Blyuss, Vincent J Gnanapragasam, Evis Sala, Tristan Barrett

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  12. [Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nikita Sushentsev *Department of Radiology, Addenbrooke's Hospital, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Box 218, Cambridge, CB2 0QQ, UK. ns784@medschl.cam.ac.uk.
Leonardo Rundo *Department of Radiology, Addenbrooke's Hospital, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Box 218, Cambridge, CB2 0QQ, UK.
Oleg BlyussSchool of Physics, Engineering & Computer Science, University of Hertfordshire, Hatfield, UK.
Vincent J GnanapragasamDivision of Urology, Department of Surgery, University of Cambridge, Cambridge, UK.
Evis SalaDepartment of Radiology, Addenbrooke's Hospital, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Box 218, Cambridge, CB2 0QQ, UK.
Tristan BarrettDepartment of Radiology, Addenbrooke's Hospital, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Box 218, Cambridge, CB2 0QQ, UK.

Funding

Cancer Research UK C197/A16465Department of Health
6 · The paper itself

Abstract

Nearly half of patients with prostate cancer (PCa) harbour low- or intermediate-risk disease considered suitable for active surveillance (AS). However, up to 44% of patients discontinue AS within the first five years, highlighting the unmet clinical need for robust baseline risk-stratification tools that enable timely and accurate prediction of tumour progression. In this proof-of-concept study, we sought to investigate the added value of MRI-derived radiomic features to standard-of-care clinical parameters for improving baseline prediction of PCa progression in AS patients. Tumour T

Indexed as

Magnetic Resonance ImagingAgedBiomarkersClinical Decision-MakingCritical PathwaysDisease ManagementDisease ProgressionHumansImage Processing, Computer-AssistedMaleMiddle AgedNeoplasm StagingPrognosisProstatic NeoplasmsRetrospective StudiesROC CurveBiomarkers

Identifiers

PMID34155265
PMCPMC8217549

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.