Evidence map›Paper›PMID 34155212›Full record

ArticleNature communications2021

A catalog of the diversity and ubiquity of bacterial microcompartments.

Markus Sutter, Matthew R Melnicki, Frederik Schulz, Tanja Woyke, Cheryl A Kerfeld

Abstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed.

  1. Review
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  3. Review
  4. bioRxiv : the preprint server for biology · 2026
    Article
  5. Review
  6. Article
  7. Architectural and biochemical advances in understanding microbial COThe Plant journal : for cell and molecular biology · 2026
    Review
  8. Article
  9. Lessons, connections, hypotheses and predictions from protein film electrochemistry.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2026
    Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Markus SutterEnvironmental Genomics and Systems Biology and Molecular Biophysics and Integrative Bioimaging Divisions, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.ORCID 0000-0001-6290-4820
Matthew R MelnickiMSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, MI, USA.
Frederik SchulzDOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.ORCID 0000-0002-4932-4677
Tanja WoykeDOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.ORCID 0000-0002-9485-5637
Cheryl A KerfeldEnvironmental Genomics and Systems Biology and Molecular Biophysics and Integrative Bioimaging Divisions, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. ckerfeld@lbl.gov.ORCID 0000-0002-9977-8482

Funding

Structure and Function of Bacterial Microcompartment Shells from Human PathogensR01AI114975 · NIAID · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI KERFELD, CHERYL A · 2015 to 2022
$3.0M
NIAID NIH HHS R01 AI114975
6 · The paper itself

Abstract

Bacterial microcompartments (BMCs) are organelles that segregate segments of metabolic pathways which are incompatible with surrounding metabolism. BMCs consist of a selectively permeable shell, composed of three types of structurally conserved proteins, together with sequestered enzymes that vary among functionally distinct BMCs. Genes encoding shell proteins are typically clustered with those for the encapsulated enzymes. Here, we report that the number of identifiable BMC loci has increased twenty-fold since the last comprehensive census of 2014, and the number of distinct BMC types has doubled. The new BMC types expand the range of compartmentalized catalysis and suggest that there is more BMC biochemistry yet to be discovered. Our comprehensive catalog of BMCs provides a framework for their identification, correlation with bacterial niche adaptation, experimental characterization, and development of BMC-based nanoarchitectures for biomedical and bioengineering applications.

Indexed as

BacteriaBacterial ProteinsCell CompartmentationGenetic LociGenetic VariationGene Transfer, HorizontalOrganellesPhylogenyBacterial Proteins

Identifiers

PMID34155212
PMCPMC8217296

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.