Evidence map›Paper›PMID 34155190›Full record

ArticleAnnals of transplantation2021

Shift in Living Kidney Donor Demographics Over the Past 50 Years in a German Transplant Center.

Claudia Sommerer, Zoi Bougioukou, Vasileios L Georgiou, Arianeb Mehrabi, Martin Zeier

Open access · greenAbstract read
In one paragraph

Article in Annals of transplantation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Long-Term Outcomes Across Age and Risk Profiles in a Caucasian Living Kidney Donor Cohort.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Claudia SommererDepartment of Nephrology, Ruprecht Karls University, Heidelberg, Germany.
Zoi BougioukouDepartment of Nephrology, Ruprecht Karls University, Heidelberg, Germany.
Vasileios L GeorgiouDepartment of Mathematics, Hellenic Open University, Patras, Greece.
Arianeb MehrabiDepartment of General, Visceral, and Transplantation Surgery, Ruprecht Karls University, Heidelberg, Germany.
Martin ZeierDepartment of Nephrology, Ruprecht Karls University, Heidelberg, Germany.
Heidelberg University · DEHellenic Open University · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Living kidney donors may face health risks after donation. Age, sex, body mass index, comorbidities, and relationship to the recipient have an impact on lifetime living kidney donor risk. In view of a changing landscape in renal transplantation with increasing organ shortages, the selection criteria for potential donors may have changed over time. MATERIAL AND METHODS We investigated donor demographics and outcomes in a cohort of 760 living kidney donors who donated from 1967 to 2016 at the transplant center in Heidelberg, Germany. RESULTS The living kidney donor age increased from 34.9±11.5 to 53.2±10.2 years, with 11.4% donors aged 65 years in the period from 2011 to 2016. The number of donors with comorbidities at the time of donation increased. The percentage of donors with a history of obesity, hypertension, smoking, and a family history of kidney disease enlarged to 18.6%, 36.1%, 37.0%, and 9.1%, respectively. De novo hypertension was a common problem in more than half of the donors at long-term follow-up, and donor renal function decreased about 30 mL/mi/1.73 m². CONCLUSIONS This detailed analysis of living kidney donor demographics over the last 50 years detected an increased proportion of donors with higher age and comorbidities today. Careful donor selection, regular follow-up visits, and systematic donor registries are required to further improve donor outcomes.

Indexed as

Kidney Failure, ChronicKidney TransplantationLiving DonorsAdultAgedDemographyFemaleGermanyHumansMaleMiddle AgedNephrectomyState MedicineYoung Adult

Identifiers

PMID34155190
PMCPMC8330426
OpenAlexW3169727186

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.