Evidence map›Paper›PMID 34155077›Full record

ArticleBMJ open2021

Individual participant data systematic reviews with meta-analyses of psychotherapies for borderline personality disorder.

Ole Jakob Storebø, Johanne Pereira Ribeiro, Mickey T Kongerslev, Jutta Stoffers-Winterling, Mie Sedoc Jørgensen, Klaus Lieb, Anthony Bateman, Richard Kirubakaran, Nicolas Dérian, Eirini Karyotaki and 2 more

Abstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ole Jakob StorebøPsychiatric Department, Region Zealand Psychiatry, Psychiatric Research Unit, Slagelse, Denmark ojst@regionsjaelland.dk.ORCID 0000-0003-0204-7745
Johanne Pereira RibeiroPsychiatric Department, Region Zealand Psychiatry, Psychiatric Research Unit, Slagelse, Denmark.ORCID 0000-0001-6019-022X
Mickey T KongerslevPsychiatric Services, Region Zealand Psychiatry, Roskilde, Denmark.
Jutta Stoffers-WinterlingDepartment of Psychiatry and Psychotherapy, University Medical Centre of the Johannes Gutenberg University Mainz, Mainz, Rheinland-Pfalz, Germany.ORCID 0000-0001-5286-8133
Mie Sedoc JørgensenPsychiatric Department, Region Zealand Psychiatry, Psychiatric Research Unit, Slagelse, Denmark.
Klaus LiebPsychiatry and Psychotherapy, University Medical Center Mainz, Mainz, Germany.
Anthony BatemanRoyal Free and University College Medical School, London, UK.
Richard KirubakaranProf BV Moses Centre for Evidence-Informed Healthcare and Health Policy, Vellore, India.
Nicolas DérianData and Development Support Unit, Region Zealand, Køge, Denmark.
Eirini KaryotakiDepartment of Clinical Psychology, VU University Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-0071-2599
Pim CuijpersDepartment of Clinical Psychology, VU University Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0001-5497-2743
Erik SimonsenPsychiatric Department, Region Zealand Psychiatry, Psychiatric Research Unit, Slagelse, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe heterogeneity in people with borderline personality disorder (BPD) and the range of specialised psychotherapies means that people with certain BPD characteristics might benefit more or less from different types of psychotherapy. Identifying moderating characteristics of individuals is a key to refine and tailor standard treatments so they match the specificities of the individual participant. The objective of this is to improve the quality of care and the individual outcomes. We will do so by performing three systematic reviews with meta-analyses of individual participant data (IPD). The aim of these reviews is to investigate potential predictors and moderating patient characteristics on treatment outcomes for patients with BPD. METHODS AND ANALYSIS: We performed comprehensive searches in 22 databases and trial registries up to October 6th 2020. These will be updated with a top-up search up until June 2021. Our primary meta-analytic method will be the one-stage random-effects approach. To identify predictors, we will use the one-stage model that accounts for interaction between covariates and treatment allocation. Heterogeneity in case-mix will be assessed with a membership model based on a multinomial logistic regression where study membership is the outcome. A random-effects meta-analysis is chosen to account for expected levels of heterogeneity. ETHICS AND DISSEMINATION: The statistical analyses will be conducted on anonymised data that have already been approved by the respective ethical committees that originally assessed the included trials. The three IPD reviews will be published in high-impact factor journals and their results will be presented at international conferences and national seminars. PROSPERO REGISTRATION NUMBER: CRD42021210688.

Indexed as

Borderline Personality DisorderData CollectionHumansMeta-Analysis as TopicPsychotherapyResearch DesignSystematic Reviews as TopicTreatment Outcomeadult psychiatrymental healthpersonality disorders

Identifiers

PMID34155077
PMCPMC8217922

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.