Evidence map›Paper›PMID 34154750›Full record

ArticleIndian heart journal

The relation between QRS complex fragmentation and segmental abnormalities of the myocardial contractility in patients with coronary artery disease.

Judith María Torales, Osmar Antonio Centurión, Nelson J Aquino, Christian O Chávez, José F Alderete, Karina E Scavenius, Orlando R Sequeira, Luis M Miño, José C Candia, Cristina Cáceres and 2 more

Open access · goldAbstract read
In one paragraph

Article in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Judith María ToralesDepartment of Cardiology, Hospital de Clínicas, Asunción National University (UNA), San Lorenzo, Paraguay; Department of Health Sciences Investigation, Sanatorio Metropolitano, Fernando de La Mora, Paraguay.
Osmar Antonio CenturiónDepartment of Cardiology, Hospital de Clínicas, Asunción National University (UNA), San Lorenzo, Paraguay; Department of Health Sciences Investigation, Sanatorio Metropolitano, Fernando de La Mora, Paraguay. Electronic address: osmarcenturion@hotmail.com.
Nelson J AquinoDepartment of Cardiology, Hospital de Clínicas, Asunción National University (UNA), San Lorenzo, Paraguay.
Christian O ChávezDepartment of Cardiology, Hospital de Clínicas, Asunción National University (UNA), San Lorenzo, Paraguay.
José F AldereteDepartment of Cardiology, Hospital de Clínicas, Asunción National University (UNA), San Lorenzo, Paraguay; Department of Health Sciences Investigation, Sanatorio Metropolitano, Fernando de La Mora, Paraguay.
Karina E ScaveniusDepartment of Cardiology, Hospital de Clínicas, Asunción National University (UNA), San Lorenzo, Paraguay; Department of Health Sciences Investigation, Sanatorio Metropolitano, Fernando de La Mora, Paraguay.
Orlando R SequeiraDepartment of Cardiology, Hospital de Clínicas, Asunción National University (UNA), San Lorenzo, Paraguay.
Luis M MiñoDepartment of Cardiology, Hospital de Clínicas, Asunción National University (UNA), San Lorenzo, Paraguay; Department of Health Sciences Investigation, Sanatorio Metropolitano, Fernando de La Mora, Paraguay.
José C CandiaDepartment of Cardiology, Hospital de Clínicas, Asunción National University (UNA), San Lorenzo, Paraguay.
Cristina CáceresDepartment of Cardiology, Hospital de Clínicas, Asunción National University (UNA), San Lorenzo, Paraguay.
Oscar A LoveraDepartment of Cardiology, Hospital de Clínicas, Asunción National University (UNA), San Lorenzo, Paraguay.
Jorge E MartínezDepartment of Cardiology, Hospital de Clínicas, Asunción National University (UNA), San Lorenzo, Paraguay.
Universidad Nacional de Asunción · PY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFragmented QRS (fQRS) is defined as any QRS complex with duration of less than 120 ms (ms) and at least one notch in the R or S wave in two or more leads belonging to the same coronary territory. The fQRS represents a delay in ventricular conduction caused by a myocardial scar associated to arrhythmic events.

methodsThis is a descriptive, retrospective, cross-sectional study of a total of 123 patientsadmitted with ischemic heart disease. The aim was to correlate the presence of fQRS in a conventional 12-leads electrocardiogram (ECG) with myocardial regional motility disorders.

resultsA total of 62% of the patients were male, the mean age was 63 ± 12 SD. fQRS was observed in 44% (64% men and 36% women), the most frequent location being the inferior wall (61%), followed by the anteroseptal and lateral walls (14% for both). Of the 36 patients with fQRS, 30 had segmental disorders, while 6 did not. Of the 45 patients without fQRS, 28 had segmental disorders, but 17 did not, which gives us a sensitivity of 52% (moderate SnNout) and specificity of 74% (high SpPin), with a positive predictive value of 83%, a negative predictive value of 38% and a prevalence of 72%.

conclusionThe presence of fQRS in the ECG has high specificity and a high positive predictive value of the existence of segmental myocardial motility disorders in patients with documented coronary artery disease.

Indexed as

Coronary Artery DiseaseAgedCross-Sectional StudiesElectrocardiographyFemaleHumansMaleMiddle AgedMyocardiumPredictive Value of TestsRetrospective StudiesCoronary artery diseaseFragmented QRS complexHypokinesiaMyocardial contractility

Identifiers

PMID34154750
PMCPMC8322790
OpenAlexW3145768492

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.