Evidence map›Paper›PMID 34154665›Full record

ArticleBMC nutrition2021

Healthy eating index patterns in adults by sex and age predict cardiometabolic risk factors in a cross-sectional study.

Virginia M Artegoitia, Sridevi Krishnan, Ellen L Bonnel, Charles B Stephensen, Nancy L Keim, John W Newman

2 registry-linked trialsAbstract read
In one paragraph

Article in BMC nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02298725 nacompletednot on this map

Individual Metabolism and Physiology Signature Study

TypeinterventionalSponsorUSDA, Western Human Nutrition Research CenterRan2014 to 2017Enrolled52ConditionsInsulin Resistance, Metabolic Syndrome X, ObesityArmsDGA Diet Plan, NHANES Diet Plan
NCT02367287 completednot on this map

Assessing the Impact of Diet on Inflammation in Healthy and Obese Adults in a Cross-Sectional Phenotyping Study

TypeobservationalSponsorUSDA, Western Human Nutrition Research CenterRan2015 to 2019Enrolled393ConditionsObesity, Inflammation
3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Lifestyle medicine pillars for women's heart health.American journal of preventive cardiology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Observational
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Virginia M ArtegoitiaObesity and Metabolism Research Unit, United States Department of Agriculture-Agricultural Research Services-Western Human Nutrition Research Center, 430 West Health Sciences Drive, Davis, CA, 95616, USA.
Sridevi KrishnanDepartment of Nutrition, University of California Davis, Davis, CA, USA.
Ellen L BonnelDepartment of Nutrition, University of California Davis, Davis, CA, USA.
Charles B StephensenDepartment of Nutrition, University of California Davis, Davis, CA, USA.
Nancy L KeimObesity and Metabolism Research Unit, United States Department of Agriculture-Agricultural Research Services-Western Human Nutrition Research Center, 430 West Health Sciences Drive, Davis, CA, 95616, USA.
John W NewmanObesity and Metabolism Research Unit, United States Department of Agriculture-Agricultural Research Services-Western Human Nutrition Research Center, 430 West Health Sciences Drive, Davis, CA, 95616, USA. john.newman2@usda.gov.ORCID http://orcid.org/0000-0001-9632-6571

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
Agricultural Research Service 2032-51530-022-00D; 2032-51530-025-00D; 2032-51530-026-00-DNCATS NIH HHS UL1 TR001860
6 · The paper itself

Abstract

backgroundAssociations between diet and cardiometabolic disease (CMD) risk may vary in men and women owing to sex differences in eating habits and physiology. The current secondary analysis sought to determine the ability of sex differences in dietary patterns to discriminate groups with or without CMD risk factors (CMDrf) in the adult population and if this was influenced by age.

methodsDiet patterns and quality were evaluated using 24 h recall-based Healthy Eating Index (HEI-2015) in free-living apparently healthy men (n = 184) and women (n = 209) 18-65 y of age with BMIs of 18-44 kg/m

resultsDiet quality increased with age in both sexes (P < 0.01), while women showed higher fruit, vegetable and saturated fat intake as a percentage of total energy (P < 0.05). The total-HEI score (i.e. diet quality) was lower in the high-CMDrf group (P = 0.01), however, diet quality parameters predicted CMDrf presence more accurately when separated by sex. Lower 'total vegetable' intake in the high-CMDrf group in both sexes, while high-CMDrf men also had lower 'total vegetables', 'greens and beans' intake, and high-CMDrf women had lower 'total fruits', 'whole-fruits', 'total vegetables', 'seafood and plant-proteins', 'fatty acids', and 'saturated fats' intakes (P < 0.05). Moreover, 'dairy' intake was higher in high-CMDrf women but not in men (sex by 'dairy' interaction P = 0.01). Sex by age diet pattern models predicted CMDrf with a 93 and 89% sensitivity and 84 and 92% specificity in women and men, respectively.

conclusionsSex and age differences in dietary patterns classified participants with and without accepted CMDrfs, supporting an association between specific diet components and CMD risk that differs by sex. Including sex specific dietary patterns into health assessments may provide targeted nutritional guidance to reduce the burden of cardiovascular disease.

trial registrationClinicalTrials.gov : NCT02367287 . ClinicalTrials.gov : NCT02298725 .

Indexed as

Cardiometabolic disease, dietary guidelines for AmericansDietary patternsHEI-2015Multivariate analysisRisk prediction

Identifiers

PMID34154665
PMCPMC8218401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.