Evidence map›Paper›PMID 34154628›Full record

Trial reportJournal of cardiothoracic surgery2021

Study on the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction.

Xiaojiao Hao, Damin Huang, Zhaoxia Wang, Jinchun Zhang, Hongqiang Liu, Yingmin Lu

Erratum issued 2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of cardiothoracic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 6 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06746233 narecruitingnot on this mapstarted 2024, after this paper: background citation

A Prospective, Randomized, Multicenter, International, Open-Label Clinical Trial Comparing Drug-Coated Balloon and Drug-Eluting Stent for the Treatment of Acute ST-Elevation Myocardial Infarction.

TypeinterventionalSponsorInstitute of Cardiovascular Diseases, VojvodinaRan2024 to 2028Enrolled598ConditionsST Elevation Myocardial Infarction (STEMI)ArmsDrug (paclitaxel) coated balloon (DCB), Second-generation Drug Eluting Stent (DES)
NCT07162792 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Safety and Efficacy of New-Generation Bioabsorbable Scaffolds Versus Drug-Coated Balloons in the Treatment of De Novo Lesions in Large Coronary Arteries: A Prospective Randomized Controlled Study

TypeinterventionalSponsorXuzhou Third People's HospitalRan2025 to 2028Enrolled150ConditionsCoronary Artery Disease(CAD), de Novo Coronary LesionsArmsbioresorbable scaffold, drug-coated balloon
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 6 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Drug Coated Balloons Versus Drug-Eluting Stents in Patients With De Novo Coronary Artery Disease.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiaojiao HaoXinhua Hospital Chongming Branch, Shanghai Jiaotong University, Nanmen Road, No. 25, Chongming District, Shanghai, 200000, China.
Damin HuangXinhua Hospital Chongming Branch, Shanghai Jiaotong University, Nanmen Road, No. 25, Chongming District, Shanghai, 200000, China.
Zhaoxia WangXinhua Hospital Chongming Branch, Shanghai Jiaotong University, Nanmen Road, No. 25, Chongming District, Shanghai, 200000, China.
Jinchun ZhangXinhua Hospital Chongming Branch, Shanghai Jiaotong University, Nanmen Road, No. 25, Chongming District, Shanghai, 200000, China.
Hongqiang LiuXinhua Hospital Chongming Branch, Shanghai Jiaotong University, Nanmen Road, No. 25, Chongming District, Shanghai, 200000, China.
Yingmin LuXinhua Hospital Chongming Branch, Shanghai Jiaotong University, Nanmen Road, No. 25, Chongming District, Shanghai, 200000, China. luym2021cn@163.com.
XinHua Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDrug-coated balloon (DCB) is a new technology that has emerged in recent years and has been proven to be effective and safe in the treatment of in-stent restenosis. The purpose of this article is to observe the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction.

methodWe selected 80 patients admitted to the hospital for STEMI from January 2018 to December 2019. The subjects were randomly divided into a Yinyi (Liaoning) Biotech Bingo Drug Coated Balloon treatment group (balloon group, n  = 38) and a drug-eluting stent (DES) treatment group (stent group, n  = 42). Patients were followed up to understand the incidence of major adverse cardiovascular events (MACE) at 1 month, 6 months and 1 year after surgery. Coronary angiography was rechecked 1 year after surgery to understand the late lumen loss (LLL) in the two groups.

resultDuring the one-year follow-up, the LLL of the target lesion in the balloon group was -0.12±0.46 mm, while the target lesion in the stent group was 0.14±0.37 mm ( P  <0.05). Within 1 year, the incidence of MACE in the balloon group was 11%, while the incidence of MACE in the stent group was 12%. There was no significant difference between the two groups. IN

conclusionWhen PCI is used for STEMI, only DCB therapy is safe and effective, and has shown good clinical effects during a one-year follow-up period.

Indexed as

Angioplasty, Balloon, CoronaryCoated Materials, BiocompatibleDrug-Eluting StentsCardiovascular DiseasesCoronary AngiographyCoronary RestenosisFemaleFollow-Up StudiesHumansMaleMiddle AgedPercutaneous Coronary InterventionST Elevation Myocardial InfarctionTreatment OutcomeCoated Materials, BiocompatibleAcute ST-segment elevation myocardial infarctionDrug-coated balloonLate lumen loss

Identifiers

PMID34154628
PMCPMC8215732
OpenAlexW3133662846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.