Trial reportThe American journal of psychiatry2021
Time Course of Relapse Following Acute Treatment for Anorexia Nervosa.
Trial report in The American journal of psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06138782 (Identifying Networks Underlying Compulsivity in Anorexia Nervosa for Targeting With Neuromodulation), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Identifying Networks Underlying Compulsivity in Anorexia Nervosa for Targeting With Neuromodulation
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Momentary physiological indices related to eating disorders: A systematic and methodological review.European eating disorders review : the journal of the Eating Disorders Association · 2024Pooled it
- Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation.Health technology assessment (Winchester, England) · 2025Trial
- Parental self-efficacy: Longitudinal impact on clinical outcomes across levels of care in adolescent anorexia nervosa.The International journal of eating disorders · 2023Trial
- Examining Facets of Body Image Disturbance Across Anorexia Nervosa Illness and Recovery Stages.European eating disorders review : the journal of the Eating Disorders Association · 2026Article
- The Use of Peripheral Parenteral Nutrition in Hospitalized Patients: A Clinical Case Series.Healthcare (Basel, Switzerland) · 2026Article
- Leveraging artificial intelligence to personalize treatment for eating disorders: A proof-of-concept study.Journal of affective disorders · 2026Article
- Moving Beyond BMI: The Need for Biomarkers of Physiological Recovery in Anorexia Nervosa and Atypical Anorexia Nervosa.The International journal of eating disorders · 2026Review
- Recovery From Anorexia Nervosa: A Concept Analysis.Journal of advanced nursing · 2026Review
- Continuity of care: time to first outpatient appointment after child and adolescent psychiatric hospital stays in Germany.BMC health services research · 2026Article
- Bridging inpatient and community treatment: feasibility, acceptability, and short-term outcomes of step care, a virtual CBT-E pathway for adults with severe eating disorders.Journal of eating disorders · 2026Article
- Learning optimal early decision treatment rules with multi-domain intermediate outcomes.Biometrics · 2026Article
- Intensive community and home-based treatments for eating disorders: a scoping review.Journal of eating disorders · 2025Review
- How and Why to Add Autonomic Phenotyping and Autonomic Balancing Interventions Into Eating Disorder Treatment.The International journal of eating disorders · 2025Article
- Genetics of Anorexia Nervosa: Translation to Future Personalized Therapies.The Psychiatric clinics of North America · 2025Review
- Target weight at discharge for children receiving their first inpatient treatment for an eating disorder.Eating and weight disorders : EWD · 2025Article
- Patient and carer feedback and engagement with ECHOMANTRA, a digital guided intervention for anorexia nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2025Article
- Zinc levels in severe eating disorders.Journal of eating disorders · 2025Article
- Article
- Applying integrated enhanced cognitive behaviour therapy (I-CBTE) to severe and longstanding eating disorders (SEED) Paper 2: An in-depth case study for clinicians.Journal of eating disorders · 2024Article
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveThere is long-standing interest in how best to define stages of illness for anorexia nervosa, including remission and recovery. The authors used data from a previously published study to examine the time course of relapse over the year following full weight restoration.
methodsFollowing weight restoration in an acute care setting, 93 women with anorexia nervosa were randomly assigned to receive fluoxetine or placebo and were discharged to outpatient care, where they also received cognitive-behavioral therapy for up to 1 year. Relapse was defined on the basis of a priori clinical criteria. Fluoxetine had no impact on the time to relapse. In the present analysis, for each day after entry into the study, the risk of relapse over the following 60 days and the following 90 days was calculated and a parametric function was fitted to approximate the Kaplan-Meier estimator.
resultsThe risk of relapse rose immediately after entry into the study, reached a peak after approximately 60 days, and then gradually declined. There was no indication of an inflection point at which the risk of relapse fell precipitously after the initial peak.
conclusionsThis analysis highlights the fact that adult patients with anorexia nervosa are at increased risk of relapse in the first months following discharge from acute care, suggesting a need for frequent follow-up and relapse prevention-focused treatment during this period. After approximately 2 months, the risk of relapse progressively decreases over time.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.