Evidence map›Paper›PMID 34153989›Full record

ReviewEuropean heart journal2021

Understanding the genetics of adult-onset dilated cardiomyopathy: what a clinician needs to know.

Upasana Tayal, James S Ware, Neal K Lakdawala, Stephane Heymans, Sanjay K Prasad

Abstract readReview
In one paragraph

Review in European heart journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
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  6. Article
  7. Sex Differences in the Genetic Causes of Dilated Cardiomyopathy.Journal of the American College of Cardiology · 2025
    Article
  8. Article
  9. Article
  10. Contemporary Insights into LMNA Cardiomyopathy.Current cardiology reports · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Observational
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Upasana TayalNational Heart Lung Institute, Imperial College London, UK.
James S WareNational Heart Lung Institute, Imperial College London, UK.ORCID 0000-0002-6110-5880
Neal K LakdawalaBrigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-6458-5421
Stephane HeymansDepartment of Cardiology, CARIM School for Cardiovascular Diseases Faculty of Health, Medicine and Life Sciences, Maastricht University, The Netherlands.
Sanjay K PrasadNational Heart Lung Institute, Imperial College London, UK.

Funding

British Heart FoundationMedical Research Council MC_UP_1102/20Wellcome Trust 107469/Z/15/Z
6 · The paper itself

Abstract

There is increasing understanding of the genetic basis to dilated cardiomyopathy and in this review, we offer a practical primer for the practising clinician. We aim to help all clinicians involved in the care of patients with dilated cardiomyopathy to understand the clinical relevance of the genetic basis of dilated cardiomyopathy, introduce key genetic concepts, explain which patients and families may benefit from genetic testing, which genetic tests are commonly performed, how to interpret genetic results, and the clinical applications of results. We conclude by reviewing areas for future research in this dynamic field.

Indexed as

Cardiomyopathy, DilatedAdultGenetic TestingHumansDilated cardiomyopathyGeneticsHeart

Identifiers

PMID34153989
PMCPMC8216730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.