Evidence map›Paper›PMID 34153815›Full record

ArticlePediatric neurology2021

Consensus Statement for the Management and Treatment of Sturge-Weber Syndrome: Neurology, Neuroimaging, and Ophthalmology Recommendations.

Sara Sabeti, Karen L Ball, Sanjoy K Bhattacharya, Elena Bitrian, Lauren S Blieden, James D Brandt, Craig Burkhart, Harry T Chugani, Stephen J Falchek, Badal G Jain and 7 more

Open access · bronzeAbstract readConsensus Statement
In one paragraph

Article in Pediatric neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 69 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 13 institutions in 1 country.

Sara SabetiDepartment of Dermatology, University of California, Irvine School of Medicine, Irvine, California.
Karen L BallThe Sturge-Weber Foundation, Houston, Texas.
Sanjoy K BhattacharyaDepartment of Ophthalmology & Bascom Palmer Eye Institute, University of Miami, Miami, Florida.
Elena BitrianDepartment of Ophthalmology & Bascom Palmer Eye Institute, University of Miami, Miami, Florida.
Lauren S BliedenDepartment of Ophthalmology & Cullen Eye Institute, Baylor College of Medicine, Houston, Texas.
James D BrandtDepartment of Ophthalmology, University of California, Davis, Sacramento, California.
Craig BurkhartDepartment of Dermatology, University of North Carolina, Chapel Hill, North Carolina.
Harry T ChuganiDepartment of Neurology, NYU School of Medicine, New York, New York.
Stephen J FalchekDepartment of Neurology, Nemours duPont Hospital for Children, Wilmington, Delaware.
Badal G JainDepartment of Neurology, Nemours duPont Hospital for Children, Wilmington, Delaware.
Csaba JuhaszDepartments of Pediatrics and Neurology, Wayne State University School of Medicine, Children's Hospital of Michigan, Detroit, Michigan.
Jeffrey A LoebDepartment of Neurology and Rehabilitation Medicine, University of Illinois at Chicago, Chicago, Illinois.
Aimee LuatDepartments of Pediatrics and Neurology, Wayne State University School of Medicine, Children's Hospital of Michigan, Detroit, Michigan; Department of Pediatrics, Central Michigan University, College of Medicine, Mt. Pleasant, Michigan.
Anna PintoDepartment of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts.
Eric SegalHackensack University Medical Center, Hackensack Meridian School of Medicine and Northeast Regional Epilepsy Group, Hackensack, New Jersey.
Jonathan SalvinPrevious affiliation Division of Pediatric Ophthalmology, Nemours duPont Hospital for Children, Wilmington, Delaware.
Kristen M KellyDepartment of Dermatology, University of California, Irvine School of Medicine, Irvine, California. Electronic address: kmkelly@uci.edu.
Community Health Systems - Dupont Hospital · USUniversity of California, Irvine · USUniversity of Miami · USBaylor College of Medicine · USBoston Children's Hospital · USCentral Michigan University · USHackensack University Medical Center · USNew York University · USSturge Weber Foundation · USUniversity of California, Davis · USUniversity of Illinois Chicago · USUniversity of North Carolina at Chapel Hill · USWayne State University · US

Funding

VCRC Administration UnitU54NS065705 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KIM, HELEN · 2009 to 2023
$20.8M
NINDS NIH HHS U54 NS065705
6 · The paper itself

Abstract

backgroundSturge-Weber syndrome (SWS) is a sporadic, neurocutaneous syndrome involving the skin, brain, and eyes. Because of the variability of the clinical manifestations and the lack of prospective studies, consensus recommendations for management and treatment of SWS have not been published.

objectiveThis article consolidates the current literature with expert opinion to make recommendations to guide the neuroimaging evaluation and the management of the neurological and ophthalmologic features of SWS.

methodsThirteen national peer-recognized experts in neurology, radiology, and ophthalmology with experience treating patients with SWS were assembled. Key topics and questions were formulated for each group and included (1) risk stratification, (2) indications for referral, and (3) optimum treatment strategies. An extensive PubMed search was performed of English language articles published in 2008 to 2018, as well as recent studies identified by the expert panel. The panel made clinical practice recommendations.

conclusionsChildren with a high-risk facial port-wine birthmark (PWB) should be referred to a pediatric neurologist and a pediatric ophthalmologist for baseline evaluation and periodic follow-up. In newborns and infants with a high-risk PWB and no history of seizures or neurological symptoms, routine screening for brain involvement is not recommended, but brain imaging can be performed in select cases. Routine follow-up neuroimaging is not recommended in children with SWS and stable neurocognitive symptoms. The treatment of ophthalmologic complications, such as glaucoma, differs based on the age and clinical presentation of the patient. These recommendations will help facilitate coordinated care for patients with SWS and may improve patient outcomes.

Indexed as

ConsensusChildChild, PreschoolCongresses as TopicGlaucomaHumansInfantInfant, NewbornNeuroimagingNeurologyOphthalmologyPort-Wine StainPractice Guidelines as TopicSeizuresSturge-Weber SyndromeConsensus statementGlaucomaPort-wine birthmarkSeizuresSturge-Weber syndrome

Identifiers

PMID34153815
PMCPMC9107097
OpenAlexW3158999051

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.