ArticleChest2021
Multimorbidity and Its Relationship With Long-Term Outcomes After Critical Care Discharge: A Prospective Cohort Study.
Article in Chest, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and representation of comorbidities and multimorbidity in randomised controlled trials in sepsis or septic shock: a systematic review.Critical care (London, England) · 2026Pooled it
- Eye movement desensitisation and reprocessing for post-traumatic stress in survivors of critical illness (EMERALD): a mixed-methods, randomised, single-blind, parallel group-controlled, feasibility trial.EClinicalMedicine · 2026Article
- Article
- Who is responsible for follow-up after critical illness? GP, ICU and patient perspectives.Critical care (London, England) · 2025Article
- What measures have been used to explore the outcomes of family members of critically ill patients: a scoping review.Intensive care medicine · 2025Article
- ICU Recovery Interventions: Is It Time for a Personalized Medicine Approach?American journal of respiratory and critical care medicine · 2025Article
- Perceptions of Hospital Care Quality According to People Living With Multiple Long-Term Conditions: A Scoping Review.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- Improving Outcomes in Survivors of Sepsis-The Transition from Secondary to Primary Care, and the Role of Primary Care: A Narrative Review.Journal of clinical medicine · 2025Review
- Impact of comorbidities on management and outcomes of patients weaning from invasive mechanical ventilation: insights from the WEAN SAFE study.Critical care (London, England) · 2025Article
- Exploring the Landscape of Social and Economic Factors in Critical Illness Survivorship: A Scoping Review.Critical care explorations · 2025Article
- Improving medication safety for intensive care patients transitioning to a hospital ward: development of a theory-informed intervention package.BMC health services research · 2024Article
- A Comparison of the Clinical Characteristics of Short-, Mid-, and Long-Term Mortality in Patients Attended by the Emergency Medical Services: An Observational Study.Diagnostics (Basel, Switzerland) · 2024Article
- Article
- Do critical illness survivors with multimorbidity need a different model of care?Critical care (London, England) · 2023Review
- Changes in Restricting Symptoms after Critical Illness among Community-Living Older Adults.American journal of respiratory and critical care medicine · 2023Article
- Patients' experiences and perspectives of post-hospital follow-up care to improve physical recovery for intensive care survivors: A systematic review of qualitative research.International journal of nursing studies advances · 2023Review
- Clin-STAR corner: Recent practice-changing studies at the interface of pulmonary and critical care medicine and geriatrics.Journal of the American Geriatrics Society · 2023Article
- Elderly Patients and Management in Intensive Care Units (ICU): Clinical Challenges.Clinical interventions in aging · 2023Review
- Long-term recovery after critical illness in older adults.Current opinion in critical care · 2022Review
- Prevalence, characteristics, and longer-term outcomes of patients with persistent critical illness attributable to COVID-19 in Scotland: a national cohort study.British journal of anaesthesia · 2022Article
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8 authors.
Funding
Abstract
backgroundSurvivors of critical illness have poor long-term outcomes with subsequent increases in health care utilization. Less is known about the interplay between multimorbidity and long-term outcomes. RESEARCH QUESTION: How do baseline patient demographics impact mortality and health care utilization in the year after discharge from critical care? STUDY DESIGN AND
methodsUsing data from a prospectively collected cohort, we used propensity score matching to assess differences in outcomes between patients with a critical care encounter and patients admitted to the hospital without critical care. Long-term mortality was examined via nationally linked data as was hospital resource use in the year after hospital discharge. The cause of death was also examined.
resultsThis analysis included 3,112 participants. There was no difference in long-term mortality between the critical care and hospital cohorts (adjusted hazard ratio, 1.09; 95% CI, 0.90-1.32; P = .39). Prehospitalization emotional health issues (eg, clinical diagnosis of depression) were associated with increased long-term mortality (hazard ratio, 1.49; 95% CI, 1.14-1.96; P < .004). Health care utilization was different between the two cohorts in the year after discharge with the critical care cohort experiencing a 29% increased risk of hospital readmission (OR, 1.29; 95% CI, 1.11-1.50; P = .001).
interpretationThis national cohort study has demonstrated increased resource use for critical care survivors in the year after discharge but fails to replicate past findings of increased longer-term mortality. Multimorbidity, lifestyle factors, and socioeconomic status appear to influence long-term outcomes and should be the focus of future research.
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