Evidence map›Paper›PMID 34152779›Full record

ArticleNano letters2021

Gold-Nanocluster-Mediated Delivery of siRNA to Intact Plant Cells for Efficient Gene Knockdown.

Huan Zhang, Yuhong Cao, Dawei Xu, Natalie S Goh, Gozde S Demirer, Stefano Cestellos-Blanco, Yuan Chen, Markita P Landry, Peidong Yang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nano letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
6.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 117 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Huan ZhangDepartment of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou, Guangdong 510632, People's Republic of China.
Yuhong CaoDepartment of Materials Science and Engineering, University of California, Berkeley, California 94720, United States.
Dawei XuDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, California 94720, United States.
Natalie S GohDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, California 94720, United States.
Gozde S DemirerDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, California 94720, United States.
Stefano Cestellos-BlancoDepartment of Materials Science and Engineering, University of California, Berkeley, California 94720, United States.
Yuan ChenPlant Gene Expression Center, United States Department of Agriculture-Agricultural Research Service, and Department of Plant and Microbial Biology, University of California Berkeley, Albany, California 94710, United States.
Markita P LandryDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, California 94720, United States.ORCID 0000-0002-5832-8522
Peidong YangDepartment of Materials Science and Engineering, University of California, Berkeley, California 94720, United States.ORCID 0000-0003-4799-1684
University of California, Berkeley · USAgricultural Research Service · USJinan University · CNLawrence Berkeley National Laboratory · USQB3 · US

Funding

Single-Molecule Imaging of Biological Trauma:Cytokine-Based Intracellular CommunicationR35GM128922 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI LANDRY, MARKITA · 2019 to 2023
$2.0M
NIGMS NIH HHS R35 GM128922US Department of Energy DE-AC02-05CH11231
6 · The paper itself

Abstract

RNA interference, which involves the delivery of small interfering RNA (siRNA), has been used to validate target genes, to understand and control cellular metabolic pathways, and to use as a "green" alternative to confer pest tolerance in crops. Conventional siRNA delivery methods such as viruses and

Indexed as

GoldPlant CellsCell Line, TumorGene Knockdown TechniquesPolyethyleneimineRNA, Small InterferingGoldPolyethyleneimineRNA, Small Interferingdeliverygene silencinggold nanoclustersplantssiRNA

Identifiers

PMID34152779
PMCPMC10539026
OpenAlexW3174317441

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.