Evidence map›Paper›PMID 34152649›Full record

ArticlePediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology2021

Mass food challenges in a vacant COVID-19 stepdown facility: Exceptional opportunity provides a model for the future.

Aideen M Byrne, Juan Trujillo, John Fitzsimons, Tariq Mohammed, Robert Ghent, Cathryn O'Carroll, David Coghlan, Jonathan O'B Hourihane, Ali Alsalemi, Aoife Cassidy and 35 more

Open access · hybridAbstract read
In one paragraph

Article in Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Direct single dose mass delabelling of antibiotic allergy in pediatrics.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  2. Allergic diseases and immunodeficiencies in children, lessons learnt from COVID-19 pandemic by 2022: A statement from the EAACI-section on pediatrics.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
    Article
  3. Article
  4. Mass food challenges in a vacant COVID-19 stepdown facility: Exceptional opportunity provides a model for the future.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2021
    Article
  5. Comments on metabolomics in asthma and atopic dermatitis, and patient care during the COVID-19 pandemic.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2021
    Article
  6. Home-based graded exposure to egg to treat egg allergy.Clinical and translational allergy · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

45 authors at 7 institutions in 1 country.

Aideen M ByrneChildren's Health Ireland, Dublin, Ireland.
Juan TrujilloCork University Hospital, Cork, Ireland.
John FitzsimonsChildren's Health Ireland, Dublin, Ireland.
Tariq MohammedMidlands Regional Hospital, Portlaoise, Ireland.
Robert GhentChildren's Health Ireland, Dublin, Ireland.
Cathryn O'CarrollChildren's Health Ireland, Dublin, Ireland.
David CoghlanChildren's Health Ireland, Dublin, Ireland.
Jonathan O'B HourihaneChildren's Health Ireland, Dublin, Ireland.ORCID 0000-0003-4997-9857
Ali AlsalemiChildren's Health Ireland, Dublin, Ireland.
Aoife CassidyChildren's Health Ireland, Dublin, Ireland.
Eva CorbetChildren's Health Ireland, Dublin, Ireland.
Rita CreightonChildren's Health Ireland, Dublin, Ireland.
Yvonne d'ArtCork University Hospital, Cork, Ireland.
Linda FarrenChildren's Health Ireland, Dublin, Ireland.
Rachel FlanaganChildren's Health Ireland, Dublin, Ireland.
Niamh FlynnChildren's Health Ireland, Dublin, Ireland.
Ruth FranklinChildren's Health Ireland, Dublin, Ireland.
Claire GrayChildren's Health Ireland, Dublin, Ireland.
Paul HardingChildren's Health Ireland, Dublin, Ireland.
Ciara HendrickChildren's Health Ireland, Dublin, Ireland.
Fionnuala HeraghtyChildren's Health Ireland, Dublin, Ireland.
Sadhbh HurleyChildren's Health Ireland, Dublin, Ireland.
Valerie KavanaghChildren's Health Ireland, Dublin, Ireland.
Dhanis LadCork University Hospital, Cork, Ireland.
Karen LeddyChildren's Health Ireland, Dublin, Ireland.
Sarah LewisChildren's Health Ireland, Dublin, Ireland.
Triona McGlynnChildren's Health Ireland, Dublin, Ireland.
Danielle O'ConnorChildren's Health Ireland, Dublin, Ireland.
Phil O'NeillHealth Service Executive, Dublin, Ireland.
Orla O'SheaChildren's Health Ireland, Dublin, Ireland.
Ann O'TooleChildren's Health Ireland, Dublin, Ireland.
Rachel QuinnChildren's Health Ireland, Dublin, Ireland.
Aisling ReidChildren's Health Ireland, Dublin, Ireland.
Alison RussellMidlands Regional Hospital, Portlaoise, Ireland.
Emma RuthChildren's Health Ireland, Dublin, Ireland.
Anne RynneChildren's Health Ireland, Dublin, Ireland.
P Bhusan SanneerappaChildren's Health Ireland, Dublin, Ireland.
Mairead SheehanChildren's Health Ireland, Dublin, Ireland.
Claire ThompsonChildren's Health Ireland, Dublin, Ireland.
Ciara TobinCork University Hospital, Cork, Ireland.
James TrayerChildren's Health Ireland, Dublin, Ireland.
Alison WallaceChildren's Health Ireland, Dublin, Ireland.
Nicola WalshChildren's Health Ireland, Dublin, Ireland.
Fiona WilsonChildren's Health Ireland, Dublin, Ireland.
Children's Health Ireland (CHI) Food Challenge Initiative Team
Children's Health Ireland at Crumlin · IECork University Hospital · IERoyal College of Surgeons in Ireland · IEMidland Regional Hospital Portlaoise · IETrinity College Dublin · IEHealth Service Executive · IEUniversity College Dublin · IE

Funding

National Treatment Purchase Fund, Ireland N/A
6 · The paper itself

Abstract

backgroundInternationally, the COVID-19 pandemic severely curtailed access to hospital facilities for those awaiting elective/semi-elective procedures. For allergic children in Ireland, already waiting up to 4 years for an elective oral food challenge (OFC), the restrictions signified indefinite delay. At the time of the initiative, there were approx 900 children on the Children's Health Ireland (CHI) waiting list. In July 2020, a project was facilitated by short-term (6 weeks) access to an empty COVID stepdown facility built, in a hotel conference centre, commandeered by the Health Service Executive (HSE), Ireland. The aim of this study was to achieve the rapid roll-out of an offsite OFC service, delivering high throughput of long waiting patients, while aligning with existing hospital policies and quality standards, international allergy guidelines and national social distancing standards.

methodsThe working group engaged key stakeholders to rapidly develop an offsite OFC facility. Consultant paediatric allergists, consultant paediatricians, trainees and allergy clinical nurse specialists were seconded from other duties. The facility was already equipped with hospital beds, bedside monitors (BP, pulse and oxygen saturation) and bedside oxygen. All medication and supplies had to be brought from the base hospital. Daily onsite consultant anaesthetic cover was resourced and a resuscitation room equipped. Standardized food challenge protocols were created. Access to the onsite hotel chef facilitated food preparation. A risk register was established.

resultsAfter 6 weeks of planning, the remote centre became operational on 7/9/2020, with the capacity of 27 OFC/day. 474 challenges were commenced: 465 (98%) were completed and 9 (2%) were inconclusive. 135 (29%) OFCs were positive, with 25 (5%) causing anaphylaxis. No child required advanced airway intervention. 8 children were transferred to the base hospital. The CHI allergy waiting list was reduced by almost 60% in only 24 days.

conclusionsOral food challenges remain a vital tool in the care of allergic children, with their cost saving and quality-of-life benefits negatively affected by a delay in their delivery. This project has shown it is possible to have huge impacts on a waiting list efficiently, effectively and safely with good planning and staff buy-in-even in a pandemic. Adoption of new, flexible and efficient models of service delivery will be important for healthcare delivery in the post-COVID-19 era.

Indexed as

COVID-19PandemicsAllergensAllergistsChildHumansSARS-CoV-2AllergensCOVID-19food allergyfood challengehealthcare delivery

Identifiers

PMID34152649
PMCPMC8420236
OpenAlexW3157757675

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.