Evidence map›Paper›PMID 34152643›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2021

A Chiral Lanthanide Tag for Stable and Rigid Attachment to Single Cysteine Residues in Proteins for NMR, EPR and Time-Resolved Luminescence Studies.

Iresha D Herath, Colum Breen, Sarah H Hewitt, Thomas R Berki, Ahmad F Kassir, Charlotte Dodson, Martyna Judd, Shereen Jabar, Nicholas Cox, Gottfried Otting and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Paramagnetic NMR to study iron sulfur proteins:Journal of biomolecular NMR · 2023
    Article
  7. Article
  8. Increasing the Modulation Depth of GdThe journal of physical chemistry letters · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Localising individual atoms of tryptophan side chains in the metallo-Magnetic resonance (Gottingen, Germany) · 2022
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Iresha D HerathResearch School of Chemistry, The Australian National University, Canberra, ACT 2605, Australia.
Colum BreenDepartment of Chemistry, Loughborough University, Epinal Way, Loughborough, LE11 3TU, UK.
Sarah H HewittDepartment of Chemistry, Loughborough University, Epinal Way, Loughborough, LE11 3TU, UK.
Thomas R BerkiDepartment of Chemistry, Loughborough University, Epinal Way, Loughborough, LE11 3TU, UK.
Ahmad F KassirDepartment of Chemistry, Loughborough University, Epinal Way, Loughborough, LE11 3TU, UK.
Charlotte DodsonDepartment of Pharmacy & Pharmacology, University of Bath Claverton Down, Bath, BA2 7AY, UK.
Martyna JuddResearch School of Chemistry, The Australian National University, Canberra, ACT 2605, Australia.
Shereen JabarResearch School of Chemistry, The Australian National University, Canberra, ACT 2605, Australia.
Nicholas CoxResearch School of Chemistry, The Australian National University, Canberra, ACT 2605, Australia.
Gottfried OttingResearch School of Chemistry, The Australian National University, Canberra, ACT 2605, Australia.
Stephen J ButlerDepartment of Chemistry, Loughborough University, Epinal Way, Loughborough, LE11 3TU, UK.ORCID http://orcid.org/0000-0001-8109-3330
Australian National University · AULoughborough University · GBUniversity of Bath · GB

Funding

Wellcome TrustWellcome Trust 204500/Z/16/Z
6 · The paper itself

Abstract

A lanthanide-binding tag site-specifically attached to a protein presents a tool to probe the protein by multiple spectroscopic techniques, including nuclear magnetic resonance, electron paramagnetic resonance and time-resolved luminescence spectroscopy. Here a new stable chiral Ln

Indexed as

Lanthanoid Series ElementsCysteineLuminescenceNuclear Magnetic Resonance, BiomolecularProteinsCysteineLanthanoid Series ElementsProteinsEPR spectroscopyFRETlanthanoid tagsluminescenceNMR spectroscopy

Identifiers

PMID34152643
PMCPMC8518945
OpenAlexW3175654748

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.