Evidence map›Paper›PMID 34152634›Full record

ArticleJournal of medical virology2021

COVID-19 sniffer dog experimental training: Which protocol and which implications for reliable sidentification?

Silvia Angeletti, Francesco Travaglino, Silvia Spoto, Maria Chiara Pascarella, Giorgia Mansi, Marina De Cesaris, Silvia Sartea, Marta Giovanetti, Marta Fogolari, Davide Plescia and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of medical virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. In search of COVID-19: The ability of biodetection canines to detect COVID-19 odours from clinical samples.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2022
    Article
  8. Extensive Connections of the Canine Olfactory Pathway Revealed by Tractography and Dissection.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Silvia AngelettiUnit of Clinical Laboratory Science, University Campus Bio-Medico of Rome, Rome, Italy.ORCID http://orcid.org/0000-0002-7393-8732
Francesco TravaglinoDepartment of Emergency, University Campus Bio-Medico of Rome, Rome, Italy.
Silvia SpotoDepartment of Diagnostic and Therapeutic Medicine, University Campus Bio-Medico of Rome, Rome, Italy.ORCID http://orcid.org/0000-0002-8799-4997
Maria Chiara PascarellaDepartment of Emergency, University Campus Bio-Medico of Rome, Rome, Italy.
Giorgia MansiDepartment of Emergency, University Campus Bio-Medico of Rome, Rome, Italy.
Marina De CesarisUnit of Clinical Laboratory Science, University Campus Bio-Medico of Rome, Rome, Italy.
Silvia SarteaHead of the Drive In Area, University Campus Bio-Medico of Rome, Rome, Italy.
Marta GiovanettiLaboratório de Flavivírus, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.ORCID http://orcid.org/0000-0002-5849-7326
Marta FogolariUnit of Clinical Laboratory Science, University Campus Bio-Medico of Rome, Rome, Italy.
Davide PlesciaK9 Unit SecurityDogs, NGS Private Security Company, Rome, Italy.
Massimiliano MaceraK9 Unit SecurityDogs, NGS Private Security Company, Rome, Italy.
Raffaele Antonelli IncalziGerontology Unit, Campus Bio Medico University and Teaching Hospital, Rome, Italy.
Massimo CiccozziUnit of Medical Statistics and Molecular Epidemiology, University Campus Bio-Medico of Rome, Rome, Italy.ORCID http://orcid.org/0000-0003-3866-9239
Università Campus Bio-Medico · ITFundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The introduction of trained sniffer dogs for COVID-19 detection could be an opportunity, as previously described for other diseases. Dogs could be trained to detect volatile organic compounds (VOCs), the whiff of COVID-19. Dogs involved in the study were three, one male and two females from different breeds, Black German Shepherd, German Shepherd, and Dutch Shepherd. The training was performed using sweat samples from SARS-CoV2 positive patients and from SARS-Cov2 free patients admitted at the University Hospital Campus Bio-medico of Rome. Gauze with sweat was collected in a glass jar with a metal top and put in metal boxes used for dog training. The dog training protocol was performed in two phases: the olfactory conditioning and the olfactory discrimination research. The training planning was focused on the switch moment for the sniffer dog, the moment when the dog was able to identify VOCs specific for COVID-19. At this time, the dog was able to identify VOCs specific for COVID-19 with significant reliability, in terms of the number of correct versus incorrect (p < 0.0001) reporting. In conclusion, this protocol could provide a useful tool for sniffer dogs' training and their introduction in a mass screening context. It could be cheaper and faster than a conventional testing method.

Indexed as

AnimalsCOVID-19DogsFemaleHumansLearningMaleMiddle AgedReproducibility of ResultsSARS-CoV-2SmellSweatVolatile Organic CompoundsWorking DogsVolatile Organic CompoundsCOVID-19dog trainingsniffer dogVOCs

Identifiers

PMID34152634
PMCPMC8426906
OpenAlexW3175637095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.