Evidence map›Paper›PMID 34152613›Full record

ArticleAllergy2021

Management of patients with atopic dermatitis undergoing systemic therapy during COVID-19 pandemic in Italy: Data from the DA-COVID-19 registry.

Andrea Chiricozzi, Marina Talamonti, Clara De Simone, Marco Galluzzo, Niccolò Gori, Gabriella Fabbrocini, Angelo Valerio Marzano, Giampiero Girolomoni, Annamaria Offidani, Maria Teresa Rossi and 33 more

Open access · bronzeAbstract read
In one paragraph

Article in Allergy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review of Teledermatology: Lessons Learned from the COVID-19 Pandemic.American journal of clinical dermatology · 2024
    Review
  6. Article
  7. Article
  8. Allergic diseases and immunodeficiencies in children, lessons learnt from COVID-19 pandemic by 2022: A statement from the EAACI-section on pediatrics.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Teledermatology in the time of COVID-19.International journal of clinical practice · 2021
    Review
  13. Mental Health Consequences of the COVID-19 Pandemic Long-Term Exposure in Italian Dermatologists.International journal of environmental research and public health · 2021
    Article
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

43 authors at 20 institutions in 2 countries.

Andrea ChiricozziDermatologia, Dipartimento Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID 0000-0002-6739-0387
Marina TalamontiDermatology Unit, Policlinico Tor Vergata, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy.
Clara De SimoneDermatologia, Dipartimento Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Marco GalluzzoDermatology Unit, Policlinico Tor Vergata, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy.
Niccolò GoriDermatologia, Dipartimento Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Gabriella FabbrociniSection of Dermatology - Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Angelo Valerio MarzanoDermatology Unit, Fondazione IRCCS Ca, Granda Ospedale Maggiore Policlinico, Milan, Italy.
Giampiero GirolomoniSection of Dermatology and Venereology, Department of Medicine, University of Verona, Verona, Italy.
Annamaria OffidaniDermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic University of the Marche Region, Ancona, Italy.
Maria Teresa RossiDepartment of Dermatology, ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy.
Luca BianchiDermatology Unit, Policlinico Tor Vergata, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy.
Antonio CristaudoClinical Dermatology, San Gallicano Dermatological Institute, Rome, Italy.
Maria Teresa FierroMedical Sciences Department, Dermatologic Clinic, University of Turin, Turin, Italy.
Luca StingeniDermatology Section, Department of Medicine, University of Perugia, Perugia, Italy.ORCID 0000-0001-7919-8141
Giovanni PellacaniDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.
Giuseppe ArgenzianoDermatology Unit, University of Campania Luigi Vanvitelli, Naples, Italy.
Annalisa PatriziDermatology UOC, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
Paolo PigattoDepartment of Biomedical, Surgical and Dental Sciences, Clinical Dermatology, IRCCS Galeazzi Orthopaedic Institute, University of Milan, Milan, Italy.
Marco RomanelliDepartment of Dermatology, University of Pisa, Pisa, Italy.
Paola SavoiaDepartment of Health Sciences, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy.
Pietro RubegniDermatology Unit, Department of Medical, Surgical and Neurosciences, University of Siena, Siena, Italy.
Caterina FotiDepartment of Biomedical Science and Human Oncology, Unit of Dermatology, University of Bari, Bari, Italy.
Nicola MilanesiDermatology Clinic, Department of Health Sciences, University of Florence, Florence, Italy.
Anna Belloni FortinaDermatology Unit - Department of Medicine DIMED, University of Padova, Padova, Italy.
Maria Rita BongiornoSection of Dermatology, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy.
Teresa GriecoUnit of Dermatology, Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.
Sergio Di NuzzoDepartment of Medicine and Surgery, Section of Dermatology, University of Parma, Parma, Italy.
Maria Concetta FargnoliDermatology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Andrea CarugnoDermatology Unit, ASST Papa Giovanni XXIII Hospital, Bergamo, Italy.ORCID 0000-0002-8231-2205
Alberico MotoleseDermatology Unit, Department of MedicalSpecialties, Arcispedale Santa Maria Nuova-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Franco RongiolettiVita-Salute San Raffaele University and IRCCS San Raffaele Hospital, Milan, Italy.
Paolo AmerioDepartment of Medicine and Aging Science, Dermatologic Clinic, G. D'Annunzio University, Chieti, Italy.
Riccardo BalestriDivision of Dermatology, Santa Chiara Hospital, Trento, Italy.
Concetta PotenzaDepartment of Medico-Surgical Sciences and Biotechnologies, Dermatology Unit, Daniele Innocenzi, Sapienza, University of Rome - Polo Pontino, Rome, Italy.
Giuseppe MicaliDermatology Clinic, University of Catania, Catania, Italy.
Cataldo PatrunoDermatology Unit, Department of Health Sciences, Università Magna Graecia, Catanzaro, Italy.
Iris ZalaudekDepartment of Dermatology, University of Trieste, Trieste, Italy.
Maurizio LombardoUnit of DermatologicalDiseases, ASST Sette Laghi, Ospedale di Circolo, Varese, Italy.
Claudio FelicianiDepartment of Medicine and Surgery, Section of Dermatology, University of Parma, Parma, Italy.
Lucia Di NardoDermatologia, Dipartimento Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Fabrizio GuarneriDermatology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Ketty PerisDermatologia, Dipartimento Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
DA‐COVID‐19 study group
Università Cattolica del Sacro Cuore · ITPoliclinico Tor Vergata · ITUniversity of Milan · ITUniversity of Parma · ITApple (Israel) · ILAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITFederico II University Hospital · ITMagna Graecia University · ITMarche Polytechnic University · ITOspedale di Circolo e Fondazione Macchi · ITOspedale Papa Giovanni XXIII · ITOspedale Santa Chiara · ITSan Gallicano Hospital · ITSanta Maria Nuova Hospital · ITSapienza University of Rome · ITUniversità Campus Bio-Medico · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITUniversity of Bari Aldo Moro · ITUniversity of Bologna · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFew and small studies have described the management of immunomodulant/immunosuppressive therapies or phototherapy in atopic dermatitis (AD) patients during coronavirus disease 2019 (COVID-19) pandemic.

methodsA national registry, named DA-COVID-19 and involving 35 Italian dermatology units, was established in order to evaluate the impact of COVID-19 pandemic on the management of adult AD patients treated with systemic immunomodulant/immunosuppressive medications or phototherapy. Demographic and clinical data were obtained at different timepoints by teledermatology during COVID-19 pandemic, when regular visits were not allowed due to sanitary restrictions. Disease severity was assessed by both physician- and patient-reported assessment scores evaluating itch intensity, sleep disturbances, and AD severity.

resultsA total of 1831 patients were included, with 1580/1831 (86.3%) continuing therapy during pandemic. Most patients were treated with dupilumab (86.1%, 1576/1831) that was interrupted in only 9.9% (156/1576) of cases, while systemic immunosuppressive compounds were more frequently withdrawn. Treatment interruption was due to decision of the patient, general practitioner, or dermatologist in 39.9% (114/286), 5.6% (16/286), and 30.1% (86/286) of cases, respectively. Fear of increased susceptibility to SARS-CoV-2 infection (24.8%, 71/286) was one of the main causes of interruption. Sixteen patients (0.9%) resulted positive to SARS-CoV-2 infection; 3 of them (0.2%) were hospitalized but no cases of COVID-related death occurred.

conclusionsMost AD patients continued systemic treatments during COVID pandemic and lockdown period, without high impact on disease control, particularly dupilumab-treated patients.

Indexed as

COVID-19Dermatitis, AtopicAdultCommunicable Disease ControlHumansItalyPandemicsRegistriesSARS-CoV-2atopic dermatitisCOVIDSARS‐CoV

Identifiers

PMID34152613
PMCPMC8014537
OpenAlexW3126828890

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.