Evidence map›Paper›PMID 34152603›Full record

ArticleClinical and experimental pharmacology & physiology2021

Thromboxane A

Yusuke Nagatani, Toshihide Higashino, Kosho Kinoshita, Hideaki Higashino

Open access · hybridAbstract read
In one paragraph

Article in Clinical and experimental pharmacology & physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. TubularInternational journal of molecular sciences · 2022
    Article
  3. Thromboxane AClinical and experimental pharmacology & physiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yusuke NagataniDepartment of Pharmacology, Kindai University School of Medicine, Osaka, Japan.
Toshihide HigashinoDepartment of Dermatology, Self Defense Forces' Central Hospital, Setagaya, Tokyo, Japan.
Kosho KinoshitaDepartment of Pharmacology, Kindai University School of Medicine, Osaka, Japan.
Hideaki HigashinoDepartment of Pharmacology, Kindai University School of Medicine, Osaka, Japan.
Kindai University · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidemiological and clinical studies have demonstrated that excessive salt intake causes severe hypertension and exacerbates organ derangement, such as in chronic kidney disease (CKD). In this study, we focused on evaluating the histological and gene expression effects in the kidneys of stroke-prone spontaneously hypertensive rats (SHRSP) with a high salt intake and the thromboxane A

Indexed as

AnimalsBridged Bicyclo CompoundsFatty Acids, MonounsaturatedHypertensionKidney DiseasesMaleRatsRats, Inbred SHRReceptors, Thromboxane A2, Prostaglandin H2Sodium ChlorideStrokeBridged Bicyclo CompoundsFatty Acids, MonounsaturatedONO 8809Receptors, Thromboxane A2, Prostaglandin H2Sodium ChlorideHypertensionONO-8809oxidative stressprostaglandin H2 receptor antagonistrenal disorderssalt-overloadstroke-prone spontaneously hypertensive ratthromboxane A2

Identifiers

PMID34152603
PMCPMC8518871
OpenAlexW3176928195

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.