Evidence map›Paper›PMID 34152286›Full record

ArticleEndocrinology, diabetes & metabolism case reports2021

Primary hepatic neuroendocrine tumor.

Le Tuan Linh, Nguyen Minh Duc, Hoang Tu Minh, Nguyen Ngoc Cuong, Vuong Thu Ha, Dao-Thi Luan, Thieu-Thi Tra My, Bui Van Lenh

Open access · goldAbstract read
In one paragraph

Article in Endocrinology, diabetes & metabolism case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

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  4. Unusual liver tumors: spectrum of imaging findings with pathologic correlationDiagnostic and interventional radiology (Ankara, Turkey) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Le Tuan LinhDepartment of Radiology, Hanoi Medical University Hospital, Hanoi, Vietnam.
Nguyen Minh DucDepartment of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh city, Vietnam.ORCID 0000-0001-5411-1492
Hoang Tu MinhDepartment of Radiology, Hanoi Medical University, Hanoi, Vietnam.
Nguyen Ngoc CuongDepartment of Radiology, Hanoi Medical University Hospital, Hanoi, Vietnam.
Vuong Thu HaDepartment of Radiology, Hanoi Medical University Hospital, Hanoi, Vietnam.
Dao-Thi LuanDepartment of Pathology, Hanoi Medical University Hospital, Hanoi, Vietnam.
Thieu-Thi Tra MyDepartment of Radiology, Hanoi Medical University, Hanoi, Vietnam.
Bui Van LenhDepartment of Radiology, Hanoi Medical University Hospital, Hanoi, Vietnam.
Hanoi Medical University · VNHanoi Medical University Hospital · VNPham Ngoc Thach University of Medicine · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

summaryPrimary hepatic neuroendocrine tumor (PHNET) is a rare type of neuroendocrine tumor (NET) that is also a primary hepatic tumor. Patients are present with almost no specific clinical symptoms and typically present with negative test results and atypical imaging characteristics; therefore, the differentiation of PHNET from other types of primary hepatic masses can be very difficult. In this article, we describe a case of PHNET that mimicked a liver helminth infection in a 57-year-old man. The diagnosis of PHNET in this patient was challenging, and the final diagnosis was based on imaging, histopathology features, and long-term follow-up. LEARNING POINTS: An uncommon type of neuroendocrine tumor (NET) is a primary hepatic neuroendocrine tumor (PHNET). Primary hepatic neuroendocrine tumors are rare NET lesions found in the liver, characterized by non-specific clinical and imaging results, which can be easily confused with other liver lesions, including HCC and parasitic lesions. To have a conclusive diagnosis and classification, a mixture of many medical assessment techniques, such as imaging, gastrointestinal endoscopy, nuclear medicine, anatomy, including histopathology, and immunohistochemistry, is essential.

Identifiers

PMID34152286
PMCPMC8240714
OpenAlexW3175661172

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.