Evidence map›Paper›PMID 34152200›Full record

ArticleJournal of bacteriology2021

A Novel PilR/PilS Two-Component System Regulates Necrotic Enteritis Pilus Production in Clostridium perfringens.

Yuanyuan Zhou, Dion Lepp, Jason Carere, Hai Yu, Chengbo Yang, Joshua Gong

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. GutMicrobiology spectrum · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yuanyuan Zhou *Guelph Research and Development Centre, Agriculture and Agri-Food Canada, Guelph, Ontario, Canada.
Dion Lepp *Guelph Research and Development Centre, Agriculture and Agri-Food Canada, Guelph, Ontario, Canada.
Jason CarereGuelph Research and Development Centre, Agriculture and Agri-Food Canada, Guelph, Ontario, Canada.
Hai YuGuelph Research and Development Centre, Agriculture and Agri-Food Canada, Guelph, Ontario, Canada.
Chengbo YangDepartment of Animal Science, University of Manitoba, Winnipeg, Manitoba, Canada.
Joshua GongGuelph Research and Development Centre, Agriculture and Agri-Food Canada, Guelph, Ontario, Canada.
Agriculture and Agri-Food Canada · CAUniversity of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clostridium perfringens causes necrotic enteritis (NE) in poultry. A chromosomal locus (VR-10B) was previously identified in NE-causing C. perfringens strains that encodes an adhesive pilus (NE pilus), along with a two-component system (TCS) designated here as PilRS. While the NE pilus is important in pathogenesis, the role of PilRS remains to be determined. The current study investigated the function of PilRS, as well as the Agr-like quorum-sensing (QS) system and VirSR TCS in the regulation of pilin production. Isogenic

Indexed as

Amino Acid SequenceAnimalsChickensClostridium perfringensCollagenEnteritisFimbriae, BacterialFimbriae ProteinsGene Expression Regulation, BacterialPoultry DiseasesSequence AlignmentVirulenceCollagenFimbriae ProteinsbindingClostridium perfringensnecrotic enteritispilusquorum sensingtwo-component regulatory system

Identifiers

PMID34152200
PMCPMC8351629
OpenAlexW3176830376

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.