Evidence map›Paper›PMID 34152145›Full record

ArticleJournal of the American Chemical Society2021

Enantioselective Iridium-Catalyzed Allylation of Nitroalkanes: Entry to β-Stereogenic α-Quaternary Primary Amines.

Woo-Ok Jung, Binh Khanh Mai, Brian J Spinello, Zachary J Dubey, Seung Wook Kim, Craig E Stivala, Jason R Zbieg, Peng Liu, Michael J Krische

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Three-ComponentOrganic letters · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Chiral Amines via Enantioselective π-Allyliridium-Accounts of chemical research · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Woo-Ok JungDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.
Binh Khanh MaiDepartment of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.ORCID 0000-0001-8487-1417
Brian J SpinelloDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.
Zachary J DubeyDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.
Seung Wook KimDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.
Craig E StivalaDiscovery Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States.ORCID 0000-0002-5024-6346
Jason R ZbiegDiscovery Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States.ORCID 0000-0002-2897-8911
Peng LiuDepartment of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.ORCID 0000-0002-8188-632X
Michael J KrischeDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0000-0001-8418-9709

Funding

Substituted Piperidine Formation via C-C Bond Forming Transfer HydrogenationR01GM069445 · NIGMS · UNIVERSITY OF TEXAS AUSTIN · PI KRISCHE, MICHAEL J · 2005 to 2024
$6.7M
Computational Models for Reactivity and Selectivity in Transition Metal-Catalyzed Olefin FunctionalizationR35GM128779 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Peng Liu · 2018 to 2026
$2.9M
Bruker AVANCE III HD 500 MHz NMRS10OD021508 · OD · UNIVERSITY OF TEXAS AT AUSTIN · PI SESSLER, JONATHAN L · 2016 to 2016
$529k
NIGMS NIH HHS R01 GM069445NIGMS NIH HHS R35 GM128779NIH HHS S10 OD021508
6 · The paper itself

Abstract

The first systematic study of simple nitronate nucleophiles in iridium-catalyzed allylic alkylation is described. Using a tol-BINAP-modified π-allyliridium

Indexed as

AlkylationAminesCatalysisCoordination ComplexesDensity Functional TheoryIridiumModels, ChemicalNitro CompoundsStereoisomerismAminesCoordination ComplexesIridiumNitro Compounds

Identifiers

PMID34152145
PMCPMC8284932

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.