ArticleCancer medicine2021
Longitudinal changes in fasting plasma glucose are associated with risk of cancer mortality: A Chinese cohort study.
Article in Cancer medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Glucose tolerance and mortality across 24 cancer types and stages: A K-CURE Nationwide registry study.Diabetes, obesity & metabolism · 2026Article
- Disease burden of lung cancer attributable to metabolic and behavioral risks in China and globally from 1990 to 2021.BMC public health · 2025Article
- Global, regional, and national burden of tracheal, bronchus, and lung cancers attributable to high fasting plasma glucose: A systematic analysis of global burden of disease 2019.Journal of diabetes · 2024Article
- 6-Year trajectory of fasting plasma glucose (FPG) and mortality risk among individuals with normal FPG at baseline: a prospective cohort study.Diabetology & metabolic syndrome · 2023Article
- Long-term fasting glucose variability and risk of cancer in patients with type 2 diabetes mellitus: A retrospective population-based cohort study in Shanghai.Journal of diabetes · 2022Article
- Differences in the impact of impaired glucose status on clinical outcomes in younger and older adults: Over a decade of follow-up in the Tehran lipid and glucose study.Frontiers in cardiovascular medicine · 2022Article
- Association of Visit-to-Visit Variability in Fasting Plasma Glucose with Digestive Cancer Risk.Oxidative medicine and cellular longevity · 2022Article
- Longitudinal changes in fasting plasma glucose are associated with risk of cancer mortality: A Chinese cohort study.Cancer medicine · 2021Article
- Association Between Obesity and Cancer Mortality: An Internal Medicine Outpatient Clinic Perspective.Journal of clinical medicine research · 2021Article
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10 authors.
Funding
Abstract
backgroundNumerous studies have suggested that fasting plasma glucose (FPG) was associated with the risk of mortality. However, relationship on longitudinal changes of FPG with the risk of mortality remained inconsistent.
methodsWe examined the association of FPG at baseline and its longitudinal changes with risk of mortality based on a cohort study in Yinzhou, China, during 2010-2018. Cox regression models and competing risk models were separately used to examine the association of FPG levels and long-term fluctuation with risk of total and cause-specific mortality.
resultsSubjects who had an impaired fasting glucose or diabetes suffered a higher risk of total mortality than subjects who had a normal fasting glucose (HRs and 95% CIs: 1.17 [1.01-1.35], 1.30 [1.10-1.53], respectively). The HR for total mortality was 1.54 (95% CI: 1.29-1.84) and for cancer mortality was 1.41 (95% CI: 1.04-1.92) in the highest quartile of coefficient of variation of FPG. Trajectory analysis indicated that subjects with a significantly changed FPG suffered a higher risk of total mortality.
conclusionAccording to this cohort study, we found that long-term fluctuation of FPG was significantly associated with the risk of total and cancer mortality. Our findings suggest that long-term fluctuation of FPG could be used as an efficient indicator for predicting the subsequent risk of mortality.
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