Evidence map›Paper›PMID 34152017›Full record

ArticleThe EMBO journal2021

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Eichi Watabe, Marina Togo-Ohno, Yuma Ishigami, Shotaro Wani, Keiko Hirota, Mariko Kimura-Asami, Sharmin Hasan, Satomi Takei, Akiyoshi Fukamizu, Yutaka Suzuki and 2 more

Open access · greenAbstract read
In one paragraph

Article in The EMBO journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Structures and mechanisms of U6 snRNA mNature communications · 2025
    Article
  4. Article
  5. Review
  6. Mechanisms and rationales of SAM homeostasis.Trends in biochemical sciences · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Structures and mechanisms of the RNA mActa biochimica et biophysica Sinica · 2024
    Review
  11. Article
  12. Review
  13. Article
  14. Ghost authors revealed: The structure and function of human NWiley interdisciplinary reviews. RNA · 2023
    Review
  15. Article
  16. Article
  17. Review
  18. Systematic comparison of tools used for mNature communications · 2023
    Article
  19. Article
  20. METTL16 in human diseases: What should we do next?Open medicine (Warsaw, Poland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Eichi WatabeLaboratory of Gene Expression, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo, Japan.
Marina Togo-OhnoLaboratory of Gene Expression, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo, Japan.
Yuma IshigamiDepartment of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Tokyo, Japan.ORCID 0000-0002-5704-291X
Shotaro WaniLaboratory of Gene Expression, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo, Japan.
Keiko HirotaLife Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Tsukuba-shi, Ibaraki, Japan.
Mariko Kimura-AsamiLaboratory of Gene Expression, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo, Japan.
Sharmin HasanLaboratory of Gene Expression, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo, Japan.ORCID 0000-0002-9236-9096
Satomi TakeiLaboratory of Gene Expression, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo, Japan.
Akiyoshi FukamizuLife Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Tsukuba-shi, Ibaraki, Japan.
Yutaka SuzukiDepartment of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa-shi, Chiba, Japan.
Tsutomu SuzukiDepartment of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Tokyo, Japan.ORCID 0000-0002-9731-1731
Hidehito KuroyanagiLaboratory of Gene Expression, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo, Japan.ORCID 0000-0002-1563-1134
Tokyo Medical and Dental University · JPThe University of Tokyo · JPUniversity of Tsukuba · JP

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Alternative splicing of pre-mRNAs can regulate gene expression levels by coupling with nonsense-mediated mRNA decay (NMD). In order to elucidate a repertoire of mRNAs regulated by alternative splicing coupled with NMD (AS-NMD) in an organism, we performed long-read RNA sequencing of poly(A)

Indexed as

Alternative SplicingAnimalsCaenorhabditis elegansHomeostasisLigasesMethionine AdenosyltransferaseMethyltransferasesNonsense Mediated mRNA DecayRNA, MessengerRNA PrecursorsS-AdenosylmethionineLigasesMethionine AdenosyltransferaseMethyltransferasesRNA, MessengerRNA PrecursorsS-AdenosylmethionineCaenorhabditis elegansmachine learningN6-methyladenosinenanopore direct RNA sequencingS-adenosyl-L-methionine synthetase

Identifiers

PMID34152017
PMCPMC8280822
OpenAlexW3176201285

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.