ArticleInternational journal of epidemiology2021
Constructing and adjusting estimates for household transmission of SARS-CoV-2 from prior studies, widespread-testing and contact-tracing data.
Article in International journal of epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 22 citations in OpenAlex.
- Exploring indoor and outdoor dust as a potential tool for detection and monitoring of COVID-19 transmission.iScience · 2024Article
- Interferon β-1a ring prophylaxis to reduce household transmission of SARS-CoV-2: a cluster randomised clinical trial.EClinicalMedicine · 2023Article
- COVID-19-related hospital admission in spouses of partners in at-risk occupations.Scandinavian journal of work, environment & health · 2023Article
- Use of surveillance data to elucidate household clustering of SARS-CoV-2 in Fulton County, Georgia a major metropolitan area.Annals of epidemiology · 2022Article
- Transmissibility of SARS-CoV-2 B.1.1.214 and Alpha Variants during 4 COVID-19 Waves, Kyoto, Japan, January 2020-June 2021.Emerging infectious diseases · 2022Article
- Virology and immune dynamics reveal high household transmission of ancestral SARS-CoV-2 strain.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022Article
- Quantifying SARS-CoV-2 Infection Risk Within the Google/Apple Exposure Notification Framework to Inform Quarantine Recommendations.Risk analysis : an official publication of the Society for Risk Analysis · 2022Article
- The COVID HOME study research protocol: Prospective cohort study of non-hospitalised COVID-19 patients.PloS one · 2022Observational
- Lessons from a pandemic.PLOS global public health · 2022Article
- COVID-19 Workplace Outbreaks by Industry Sector and Their Associated Household Transmission, Ontario, Canada, January to June, 2020.Journal of occupational and environmental medicine · 2021Article
- Serial population-based serosurveys for COVID-19 in two neighbourhoods of Karachi, Pakistan.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021Article
- Attitudes and Commitment Toward Precautionary Measures Against COVID-19 Amongst the Jordanian Population: A Large-Scale Cross-Sectional Survey.Frontiers in public health · 2021Article
- Household transmission of SARS-CoV-2: a systematic review and meta-analysis of secondary attack rate.medRxiv : the preprint server for health sciences · 2020Article
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWith reduced community mobility, household infections may become increasingly important in SARS-CoV-2 transmission dynamics.
methodsWe investigate the intra-household transmission of COVID-19 through the secondary-attack rate (SAR) and household reproduction number (Rh). We estimate these using (i) data from 29 prior studies (February-August 2020), (ii) epidemiologically linked confirmed cases from Singapore (January-April 2020) and (iii) widespread-testing data from Vo' (February-March 2020). For (i), we use a Bayesian random-effects model that corrects for reverse transcription-polymerase chain reaction (RT-PCR) test sensitivity and asymptomatic cases. We investigate the robustness of Rh with respect to community transmission rates and mobility patterns.
resultsThe corrected pooled estimates from prior studies for SAR and Rh are 24% (20-28%) and 0.34 (0.30-0.38), respectively. Without corrections, the pooled estimates are: SAR = 18% (14-21%) and Rh = 0.28 (0.25-0.32). The corrected estimates line up with direct estimates from contact-tracing data from Singapore [Rh = 0.32 (0.22-0.42)] and population testing data from Vo' [SAR = 31% (28-34%) and Rh = 0.37 (0.34-0.40)]. The analysis of Singapore data further suggests that the value of Rh (0.22-0.42) is robust to community-spread dynamics; our estimate of Rh stays constant whereas the fraction of infections attributable to household transmission (Rh/Reff) is lowest during outbreaks (5-7%) and highest during lockdowns and periods of low community spread (25-30%).
conclusionsThe three data-source types yield broadly consistent estimates for SAR and Rh. Our study suggests that household infections are responsible for a large fraction of infections and so household transmission may be an effective target for intervention.
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