ArticleJournal of X-ray science and technology2021
Radiation dose estimation for pencil beam X-ray luminescence computed tomography imaging.
Article in Journal of X-ray science and technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- Correlation between X-ray tube current exposure time and X-ray photon number in GATE.Journal of X-ray science and technology · 2022Article
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2 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPencil beam X-ray luminescence computed tomography (XLCT) imaging provides superior spatial resolution than other imaging geometries like sheet beam and cone beam geometries. However, the pencil beam geometry suffers from long scan times, resulting in concerns overdose which discourages the use of pencil beam XLCT.
objectiveThe dose deposited in pencil beam XLCT imaging was investigated to estimate the dose from one angular projection scan with three different X-ray sources. The dose deposited in a typical small animal XLCT imaging was investigated.
methodsA Monte Carlo simulation platform, GATE (Geant4 Application for Tomographic Emission) was used to estimate the dose from one angular projection scan of a mouse leg model with three different X-ray sources. Dose estimations from a six angular projection scan by three different X-ray source energies were performed in GATE on a mouse trunk model composed of muscle, spine bone, and a tumor.
resultsWith the Sigray source, the bone marrow of mouse leg was estimated to have a radiation dose of 44 mGy for a typical XLCT imaging with six angular projections, a scan step size of 100 micrometers, and 106 X-ray photons per linear scan. With the Sigray X-ray source and the typical XLCT scanning parameters, we estimated the dose of spine bone, muscle tissues, and tumor structures of the mouse trunk were 38.49 mGy, 15.07 mGy, and 16.87 mGy, respectively.
conclusionOur results indicate that an X-ray benchtop source (like the X-ray source from Sigray Inc.) with high brilliance and quasi-monochromatic properties can reduce dose concerns with the pencil beam geometry. Findings of this work can be applicable to other imaging modalities like X-ray fluorescence computed tomography if the imaging protocol consists of the pencil beam geometry.
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