Evidence map›Paper›PMID 34151742›Full record

ArticleEpigenetics2022

Teresa Infante, Monica Franzese, Antonio Ruocco, Concetta Schiano, Ornella Affinito, Katia Pane, Domenico Memoli, Francesca Rizzo, Alessandro Weisz, Paola Bontempo and 5 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Epigenetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04371809 (DNA Methylation Analysis to Identify Functional Epigenetic Marks in Acute Coronary Syndrome and Atrial Fibrillation), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04371809 completednot on this map

DNA Methylation Analysis to Identify Functional Epigenetic Marks in Acute Coronary Syndrome and Atrial Fibrillation: DIANA Clinical Trial

TypeobservationalSponsorUniversity of Campania Luigi VanvitelliRan2019 to 2022Enrolled100ConditionsCoronary Artery Disease, Acute Coronary Syndrome, Atrial FibrillationArmsDNA methylome
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Association Between Circulating CD4Journal of cardiovascular translational research · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. [Association betweenNan fang yi ke da xue xue bao = Journal of Southern Medical University
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Teresa InfanteDepartment of Advanced Medical and Surgical Sciences (DAMSS), University of Campania "Luigi Vanvitelli", Naples, Italy.
Monica FranzeseIRCCS SDN, Naples, Italy.
Antonio RuoccoUnit of Cardiovascular Diseases and Arrhythmias, "Antonio Cardarelli" Hospital, Naples, Italy.
Concetta SchianoDepartment of Advanced Medical and Surgical Sciences (DAMSS), University of Campania "Luigi Vanvitelli", Naples, Italy.
Ornella AffinitoIRCCS SDN, Naples, Italy.
Katia PaneIRCCS SDN, Naples, Italy.
Domenico MemoliDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana," University of Salerno, Baronissi, SA, Italy.
Francesca RizzoDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana," University of Salerno, Baronissi, SA, Italy.
Alessandro WeiszDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana," University of Salerno, Baronissi, SA, Italy.
Paola BontempoDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Vincenzo GrimaldiIRCCS SDN, Naples, Italy.ORCID 0000-0002-1377-8220
Liberato BerrinoDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Andrea SoricelliIRCCS SDN, Naples, Italy.
Ciro MauroUnit of Cardiovascular Diseases and Arrhythmias, "Antonio Cardarelli" Hospital, Naples, Italy.
Claudio NapoliDepartment of Advanced Medical and Surgical Sciences (DAMSS), University of Campania "Luigi Vanvitelli", Naples, Italy.ORCID 0000-0002-5455-555X
University of Campania "Luigi Vanvitelli" · ITSDN Istituto di Ricerca Diagnostica e Nucleare · ITUniversity of Salerno · ITParthenope University of Naples · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute coronary syndrome (ACS) is the most severe clinical manifestation of coronary heart disease.We performed an epigenome-wide analysis of circulating CD4

Indexed as

Acute Coronary SyndromeDNA MethylationATP Binding Cassette Transporter 1CD8-Positive T-LymphocytesEpigenesis, GeneticHumansNFATC Transcription FactorsPilot ProjectsT Cell Transcription Factor 1Transcription FactorsABCA1 protein, humanATP Binding Cassette Transporter 1NFATC1 protein, humanNFATC Transcription FactorsT Cell Transcription Factor 1TCF7 protein, humanTranscription FactorsAcute coronary syndromeDNA methylationepigeneticsT lymphocytes

Identifiers

PMID34151742
PMCPMC9067513
OpenAlexW3176623722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.