ArticleJournal of the American Heart Association2021
Functional Assessment of Myocardial Bridging With Conventional and Diastolic Fractional Flow Reserve: Vasodilator Versus Inotropic Provocation.
Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 52 citations in OpenAlex.
- Exertional Syncope Caused by Hemodynamically Significant Myocardial Bridging With Coronary Vasospasm.JACC. Case reports · 2026Article
- Evaluation and Treatment of Myocardial Bridging by Clinical Phenotype.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Review
- Clinical use of coronary computed tomography angiography-derived fractional flow reserve: expert consensus by an International Working Group.European radiology · 2026Article
- Review
- Multimodality Approach to Coronary Ischemic Testing in Pediatric Patients: A Scientific Statement From the American Heart Association.Journal of the American Heart Association · 2026Review
- Coronary artery bypass grafting may not be suitable in pure myocardial bridging: a case report.European heart journal. Case reports · 2026Article
- Predicting recurrent chest pain in patients with myocardial bridging using explainable machine learning: a multicenter study integrating CT-derived functional and inflammatory imaging biomarkers.BMC medical imaging · 2026Article
- Intracoronary Full Physiology and Imaging Unveiling a Rare Cause of MINOCA Presenting as Ventricular Fibrillation.JACC. Case reports · 2025Article
- Cardiac cycle weighted ΜQFR for the assessment of functional relevance of the myocardial bridge.The international journal of cardiovascular imaging · 2025Article
- Interplay Between Myocardial Bridging, Atherosclerosis, and Spasm in Patients With Nonobstructive Coronary Arteries.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- Coronary Endothelial Dysfunction and Vasomotor Dysregulation in Myocardial Bridging.Journal of cardiovascular development and disease · 2025Review
- Prevalence of Coronary Microvascular Dysfunction and Epicardial Spasm in Patients With Angina and Myocardial Bridge.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Article
- Myocardial ischemia caused by the synergistic effect of myocardial bridge and moderate stenosis: case report.BMC cardiovascular disorders · 2024Article
- Prognostic Implications of Resistive Reserve Ratio in Patients With Nonobstructive Coronary Artery Disease With Myocardial Bridging.Journal of the American Heart Association · 2024Article
- Coronary vasospasm and cardiovascular outcomes in patients with isolated myocardial bridging: A retrospective study.Cardiology journal · 2024Article
- Dynamic perfusion SPECT for functional evaluation in symptomatic patients with myocardial bridging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Myocardial Bridging: Review on the Role of Coronary Computed Tomography Angiography.Journal of clinical medicine · 2023Review
- Managing Myocardial Bridge and Right Ventricular Outflow Tract Obstruction in an Adolescent With Hypertrophic Cardiomyopathy.World journal for pediatric & congenital heart surgery · 2023Article
- Nomogram to predict recurrent chest pain in patients with myocardial bridging.European radiology · 2023Article
- MINOCA Associated with a Myocardial Bridge: Pathogenesis, Diagnosis and Treatment.Journal of clinical medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Functional assessment of myocardial bridging (MB) remains clinically challenging because of the dynamic nature of the extravascular coronary compression with a certain degree of intraluminal coronary reduction. The aim of our study was to assess performance and diagnostic value of diastolic-fractional flow reserve (d-FFR) during dobutamine provocation versus conventional-FFR during adenosine provocation with exercise-induced myocardial ischemia as reference. Methods and Results This prospective study includes 60 symptomatic patients (45 men, mean age 57±9 years) with MB on the left anterior descending artery and systolic compression ≥50% diameter stenosis. Patients were evaluated by exercise stress-echocardiography test, and both conventional-FFR and d-FFR in the distal segment of left anterior descending artery during intravenous infusion of adenosine (140 μg/kg per minute) and dobutamine (10-50 μg/kg per minute), separately. Exercise-stress-echocardiography test was positive for myocardial ischemia in 19/60 patients (32%). Conventional-FFR during adenosine and peak dobutamine had similar values (0.84±0.04 versus 0.84±0.06,
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.