Evidence map›Paper›PMID 34151565›Full record

ArticleBiomacromolecules2021

Three-Dimensional Printable Conductive Semi-Interpenetrating Polymer Network Hydrogel for Neural Tissue Applications.

Chiara Rinoldi, Massimiliano Lanzi, Roberto Fiorelli, Paweł Nakielski, Krzysztof Zembrzycki, Tomasz Kowalewski, Olga Urbanek, Valentina Grippo, Katarzyna Jezierska-Woźniak, Wojciech Maksymowicz and 5 more

Abstract read
In one paragraph

Article in Biomacromolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

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  10. RSC advances · 2025
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  13. Influence of conductive carbon and MnCoBeilstein journal of nanotechnology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Chiara RinoldiDepartment of Biosystems and Soft Matter, Institute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw 02-106, Poland.
Massimiliano LanziDepartment of Industrial Chemistry "Toso Montanari", Alma Mater Studiorum University of Bologna, Bologna 40136, Italy.ORCID 0000-0002-2466-2813
Roberto FiorelliIvy Brain Tumor Center, Barrow Neurological Institute, Phoenix, Arizona 85013, United States.
Paweł NakielskiDepartment of Biosystems and Soft Matter, Institute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw 02-106, Poland.
Krzysztof ZembrzyckiDepartment of Biosystems and Soft Matter, Institute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw 02-106, Poland.
Tomasz KowalewskiDepartment of Biosystems and Soft Matter, Institute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw 02-106, Poland.
Olga UrbanekLaboratory of Polymers and Biomaterials, Institute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw 02-106, Poland.
Valentina GrippoFaculty of Chemistry, University of Warsaw, Warsaw 02-093, Poland.
Katarzyna Jezierska-WoźniakDepartment of Neurology and Neurosurgery, University of Warmia and Mazury in Olsztyn, Olsztyn 11-041, Poland.
Wojciech MaksymowiczDepartment of Neurology and Neurosurgery, University of Warmia and Mazury in Olsztyn, Olsztyn 11-041, Poland.
Andrea CamposeoNEST, Istituto Nanoscienze CNR and Scuola Normale Superiore, Pisa 56127, Italy.
Renata BilewiczFaculty of Chemistry, University of Warsaw, Warsaw 02-093, Poland.ORCID 0000-0003-0058-3691
Dario PisignanoNEST, Istituto Nanoscienze CNR and Scuola Normale Superiore, Pisa 56127, Italy.ORCID 0000-0003-3758-5199
Nader SanaiIvy Brain Tumor Center, Barrow Neurological Institute, Phoenix, Arizona 85013, United States.
Filippo PieriniDepartment of Biosystems and Soft Matter, Institute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw 02-106, Poland.ORCID 0000-0002-6526-4141

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrinsically conducting polymers (ICPs) are widely used to fabricate biomaterials; their application in neural tissue engineering, however, is severely limited because of their hydrophobicity and insufficient mechanical properties. For these reasons, soft conductive polymer hydrogels (CPHs) are recently developed, resulting in a water-based system with tissue-like mechanical, biological, and electrical properties. The strategy of incorporating ICPs as a conductive component into CPHs is recently explored by synthesizing the hydrogel around ICP chains, thus forming a semi-interpenetrating polymer network (semi-IPN). In this work, a novel conductive semi-IPN hydrogel is designed and synthesized. The hybrid hydrogel is based on a poly(

Indexed as

HydrogelsNerve TissueElectric ConductivityPolymersTissue EngineeringHydrogelsPolymers

Identifiers

PMID34151565
PMCPMC8462755

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.