ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2022
Pathogenesis of sporadic Alzheimer's disease by deficiency of NMDA receptor subunit GluN3A.
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In one paragraph
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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0cells of the map it votes in
31citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 26 citations in OpenAlex.
- Synaptic vs. Non-Synaptic Glycine Receptors: Physiological Role and Implications in Alzheimer's Disease Pathology.International journal of molecular sciences · 2026Review
- Memantine: updates from the past decade and implications for future novel therapeutic applications.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Non-classical NMDAR subunit GluN3A in a specialized hippocampal region regulates stress-coping strategies in male mice.Communications biology · 2026Article
- Article
- Genetic modifiers of APOE-ε4-associated cognitive decline.Nature communications · 2026Article
- The GluN3-containing NMDA receptors.Channels (Austin, Tex.) · 2025Review
- Molecular mechanisms of excitotoxicity and their relevance to the pathogenesis of neurodegenerative diseases-an update.Acta pharmacologica Sinica · 2025Review
- Article
- Discovery of novel GluN1/GluN3A NMDA receptor inhibitors using a deep learning-based method.Acta pharmacologica Sinica · 2025Article
- Alzheimer's Disease: From Molecular Mechanisms to Promising Therapeutic Strategies.International journal of molecular sciences · 2025Review
- Comprehensive characterization of the RNA editing landscape in the human aging brains with Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Blocking TRPM4 alleviates pancreatic acinar cell damage via an NMDA receptor-dependent pathway in acute pancreatitis.Theranostics · 2025Article
- Hippocampal tau-induced GRIN3A deficiency in Alzheimer's disease.FEBS open bio · 2024Article
- From Fundamentals to Innovation in Alzheimer's Disease: Molecular Findings and Revolutionary Therapies.International journal of molecular sciences · 2024Review
- GluN3A and Excitatory Glycine Receptors in the Adult Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Recent advances in Alzheimer's disease: Mechanisms, clinical trials and new drug development strategies.Signal transduction and targeted therapy · 2024Review
- TargetingInternational journal of molecular sciences · 2024Review
- Recent Advancements in the Treatment of Alzheimer's Disease: A Multitarget-directed Ligand Approach.Current medicinal chemistry · 2024Review
- Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice.Frontiers in aging neuroscience · 2024Article
- Alzheimer's disease: a comprehensive review of epidemiology, risk factors, symptoms diagnosis, management, caregiving, advanced treatments and associated challenges.Frontiers in medicine · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Weiwei ZhongDepartment of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia, USA.
Anika WuDepartment of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia, USA.
Ken BerglundCenter for Visual and Neurocognitive Rehabilitation, Department of Veteran's Affair, Atlanta VA Medical Center, Decatur, Georgia, USA.
Xiaohuan GuDepartment of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia, USA.
Michael Qize JiangDepartment of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia, USA.
Jay TalatiDepartment of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia, USA.
Jingjie ZhaoDepartment of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia, USA.
Ling WeiDepartment of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia, USA.
Shan Ping YuDepartment of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0003-1335-1398
Emory University · USAtlanta VA Medical Center · US
Funding
ENNCF - Viral Vector CoreP30NS055077 · NINDS · EMORY UNIVERSITY · PI BASSELL, GARY J · 2008 to 2018
$6.8MDirect Reprogramming of the brain after ischemic stroke in the aged mouseR01NS114221 · NINDS · EMORY UNIVERSITY · PI WEI, LING, YU, SHAN P. · 2020 to 2024
$2.0MApplication of optogenetics in iPS cell transplantation therapy for ischemic stroR01NS085568 · NINDS · EMORY UNIVERSITY · PI GROSS, ROBERT E, WEI, LING · 2014 to 2018
$1.7MStem cell transplantation therapy via intranasal delivery after strokeR01NS091585 · NINDS · EMORY UNIVERSITY · PI WEI, LING · 2016 to 2020
$1.7MCreating Endogenous Stem Cell Niches to Promote Functional Brain Repair Post-TBIR01NS099596 · NINDS · UNIVERSITY OF GEORGIA · PI KARUMBAIAH, LOHITASH · 2017 to 2021
$1.6MNeuroprotection NR3A in Cultured Neurons and Ischemic NeonatesR01NS057255 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI YU, SHAN P. · 2007 to 2011
$1.1MAcquisition of an integrated multi-photon live imaging system for simultaneous in vitro and in vivo electrophysiologyS10OD021773 · OD · EMORY UNIVERSITY · PI BERGLUND, KEN · 2017 to 2017
$600kNovel Regenerative Treatment of TBI and Post TBI DepressionI01RX002473 · VA · VETERANS HEALTH ADMINISTRATION · PI YU, SHAN P. · 2018 to 2022
–NIH HHS S10 OD021773NINDS NIH HHS P30 NS055077NINDS NIH HHS R01 NS057255NINDS NIH HHS R01 NS085568NINDS NIH HHS R01 NS091585NINDS NIH HHS R01 NS099596NINDS NIH HHS R01 NS114221RRD VA I01 RX002473
Abstract
The Ca
Indexed as
Alzheimer DiseaseReceptors, N-Methyl-D-AspartateAnimalsHumansMemantineMiceMice, KnockoutNeuronsGluN3A protein, mouseGRIN3A protein, humanMemantineReceptors, N-Methyl-D-AspartateAlzheimer's diseasedegenerative excitotoxicitydementiaN-methyl-d-aspartate receptorNR3Apreventionsubhealth status
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.