ArticleJournal of applied clinical medical physics2021
Commissioning of and preliminary experience with a new fully integrated computed tomography linac.
Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 40 citations in OpenAlex.
- Diagnostic CT-guided online adaptive radiotherapy for locally advanced colon cancer: a prospective implementation and feasibility study.Clinical and translational radiation oncology · 2026Article
- Novel extended field-of-view reconstruction algorithms in computed tomography simulation for imaging and volumetric modulated arc therapy dosimetry.Quantitative imaging in medicine and surgery · 2026Article
- Real-Time AI-Based Radiotherapy Planning for Nasopharyngeal Carcinoma: Development and Validation.Cyborg and bionic systems (Washington, D.C.) · 2026Article
- Dosimetric validation of biaxially rotational dynamic-radiation therapy using an O-ring linear accelerator.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2026Article
- A comparative dosimetric evaluation of two image-guided calibration strategies for multi-isocenter total body irradiation: integrated fan-beam CT-based alignment versus sequential cone-beam CT-guided localization.Frontiers in oncology · 2026Article
- Assessment of the mechanical performance of a novel CT-linac treatment couch.Frontiers in oncology · 2026Article
- An all-in-one workflow for emergency hippocampal-avoidance whole-brain radiotherapy in brain metastases, with optional online adaptive extension.Journal of applied clinical medical physics · 2025Article
- CT-based auto-segmentation of multiple target volumes for all-in-one radiotherapy in rectal cancer patients.Radiation oncology (London, England) · 2025Article
- A study of criteria-based online adaptive radiotherapy with radiomics and dosimetry for postoperative prostate cancer.Medical physics · 2025Article
- Real-time morphological and dosimetric adaptation in nasopharyngeal carcinoma radiotherapy: insights from autosegmented fractional fan-beam CT.Radiation oncology (London, England) · 2025Article
- Validation of in vivo dose using EPID combined with fan-beam CT guidance in post-breast-conserving radiotherapy for early-stage breast cancer.BMC cancer · 2025Article
- Risk assessment and quality management in AIO based on CT-linac for nasopharyngeal carcinoma: An improved FMEA and FTA approach.Medical physics · 2025Article
- Does deformation of immobilization devices impact treatment accuracy in thoracic cancer radiotherapy?Journal of applied clinical medical physics · 2025Article
- Evaluating the Implementation of fan-beam CT-guided online adaptive re-planning in definitive cervical cancer radiotherapy.Frontiers in oncology · 2025Article
- Validation of SRS MapCHECK for CyberKnife patient-specific quality assurance: challenges with small cone sizes.Frontiers in oncology · 2025Article
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- Evaluation of bladder filling effects on the dose distribution during radiotherapy for cervical cancer based on daily CT images.Journal of applied clinical medical physics · 2023Article
- Geometric and dosimetric evaluation of deep learning based auto-segmentation for clinical target volume on breast cancer.Journal of applied clinical medical physics · 2023Article
- Fan beam CT-guided online adaptive external radiotherapy of uterine cervical cancer: a dosimetric evaluation.BMC cancer · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
purposeA new medical linear accelerator (linac) platform integrated with helical computed tomography (CT), the uRT-linac 506c, was introduced into clinical application in 2019 by United Imaging Healthcare (UIH) Co., Ltd. (Shanghai, China). It combines a Carm linac with a diagnostic-quality 16-slice CT imager, providing seamless workflow from simulation to treatment. The aim of this report is to assess the technical characteristics, commissioning results and preliminary experiences stemming from clinical usage.
methodsThe mechanical and imaging test procedures, commissioning data collection and TPS validation were summarized. CTIGRT accuracy was investigated with different loads and couch extensions. A series of end-to-end cases for different treatment sites and delivery techniques were tested preclinically to estimate the overall accuracy for the entire treatment scheme. The results of patient-specific QA and machine stability during a one-year operation are also reported.
resultsGantry/couch/collimator isocentricity was measured as 0.63 mm in radius. The TPS models were in agreement with the beam commissioning data within a deviation of 2%. An overall submillimeter accuracy was demonstrated for the CT-IGRT process under all conditions. The absolute point dose difference for all the preclinical end-to-end tests was within 3%, and the gamma passing rate of the 2D dose distribution measured by EBT3 film was better than 90% (3% DD, 3 mm DTA and 10% threshold). Pretreatment QA of clinical cases resulted with better than 3% point dose difference and more than 99% gamma passing rate (3% DD/2 mm DTA/10% threshold) tested with Delta4. The output of the linac was mostly within 1% of variation in a one-year operation.
conclusionThe commissioning results and clinical QA results show that the uRT-linac 506c platform exhibits good and stable performance in mechanical and dosimetric accuracy. The integrated CT system provides an efficient workflow for image guidance with submillimeter localization precision, and will be a good starting point to proceed advanced adaptive radiotherapy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.