Evidence map›Paper›PMID 34151504›Full record

ArticleJournal of applied clinical medical physics2021

Commissioning of and preliminary experience with a new fully integrated computed tomography linac.

Lei Yu, Jun Zhao, Zhen Zhang, Jiazhou Wang, Weigang Hu

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 40 citations in OpenAlex.

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  4. Dosimetric validation of biaxially rotational dynamic-radiation therapy using an O-ring linear accelerator.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lei YuDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Jun ZhaoDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Zhen ZhangDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Jiazhou WangDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Weigang HuDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Shanghai Medical College of Fudan University · CNFudan University Shanghai Cancer Center · CN

Funding

Funding of Shanghai Committee of Science and Technology 19DZ1930902
6 · The paper itself

Abstract

purposeA new medical linear accelerator (linac) platform integrated with helical computed tomography (CT), the uRT-linac 506c, was introduced into clinical application in 2019 by United Imaging Healthcare (UIH) Co., Ltd. (Shanghai, China). It combines a Carm linac with a diagnostic-quality 16-slice CT imager, providing seamless workflow from simulation to treatment. The aim of this report is to assess the technical characteristics, commissioning results and preliminary experiences stemming from clinical usage.

methodsThe mechanical and imaging test procedures, commissioning data collection and TPS validation were summarized. CTIGRT accuracy was investigated with different loads and couch extensions. A series of end-to-end cases for different treatment sites and delivery techniques were tested preclinically to estimate the overall accuracy for the entire treatment scheme. The results of patient-specific QA and machine stability during a one-year operation are also reported.

resultsGantry/couch/collimator isocentricity was measured as 0.63 mm in radius. The TPS models were in agreement with the beam commissioning data within a deviation of 2%. An overall submillimeter accuracy was demonstrated for the CT-IGRT process under all conditions. The absolute point dose difference for all the preclinical end-to-end tests was within 3%, and the gamma passing rate of the 2D dose distribution measured by EBT3 film was better than 90% (3% DD, 3 mm DTA and 10% threshold). Pretreatment QA of clinical cases resulted with better than 3% point dose difference and more than 99% gamma passing rate (3% DD/2 mm DTA/10% threshold) tested with Delta4. The output of the linac was mostly within 1% of variation in a one-year operation.

conclusionThe commissioning results and clinical QA results show that the uRT-linac 506c platform exhibits good and stable performance in mechanical and dosimetric accuracy. The integrated CT system provides an efficient workflow for image guidance with submillimeter localization precision, and will be a good starting point to proceed advanced adaptive radiotherapy.

Indexed as

Particle AcceleratorsRadiotherapy Planning, Computer-AssistedChinaHumansPhantoms, ImagingRadiometryTomography, X-Ray Computedbeam commissioningCT-based IGRTfully integrated CT-linac

Identifiers

PMID34151504
PMCPMC8292712
OpenAlexW3176938214

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.