Evidence map›Paper›PMID 34151309›Full record

ArticleAmerican heart journal plus : cardiology research and practice2021

Association of patient-reported outcomes with hospitalization risk in atrial fibrillation.

Yimin Chen, Tarryn Tertulien, Andrew D Althouse, Amber Johnson, Brittany Gisi, Jared W Magnani

Open access · goldAbstract read
In one paragraph

Article in American heart journal plus : cardiology research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yimin Chen *Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Tarryn Tertulien *Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Andrew D AlthouseDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Amber JohnsonDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Brittany GisiDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, USA.
Jared W MagnaniDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
University of Pittsburgh · USVanderbilt University Medical Center · US

Funding

Diversity Supplement for geocoding in the parent grant "A Mobile Relational Agent to Enhance Atrial Fibrillation self-care"R33HL144669 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MAGNANI, JARED W. · 2020 to 2023
$3.8M
Mobile Health intervention for rural atrial fibrillationR01HL143010 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MAGNANI, JARED W. · 2019 to 2022
$3.0M
NHLBI NIH HHS R01 HL143010NHLBI NIH HHS R33 HL144669
6 · The paper itself

Abstract

backgroundPatient-reported outcomes in atrial fibrillation (AF) are increasingly used to evaluate treatment efficacy and as endpoints in clinical trials. Few studies have related patient-reported outcomes in AF to clinical events and outcomes. We examined the association between patient-reported outcomes and hospitalization risk in individuals with AF receiving care at a regional healthcare system. METHODS AND

resultsWe related the AF Effect on QualiTy of Life (AFEQT), a validated measure (range 0-100) with higher scores indicating superior AF-specific patient-reported outcomes, to hospitalization events in a cohort with prevalent AF. We determined incidence rates for hospitalization events (all-cause, cardiac-, or AF-related) across quartiles of AFEQT scores. We used the Andersen-Gill method to account for multiple hospitalization events per individual and compared the risks of hospitalization across AFEQT quartiles in multivariable-adjusted models. In 339 individuals with AF (age 72.3 ± 10.1 years; 43% women) followed for median 2.6 years (range 0-3.4 years), we observed 417 total hospitalization events. We identified increased incidence rates of hospitalization with progressively decreased AFEQT quartile. Relative to those in the highest AFEQT quartile, individuals in the lowest AFEQT quartile had 3-fold greater risk of all-cause hospitalization (95% Confidence Interval [CI] 1.67-6.57,

conclusionsWe identified a progressive association between patient-reported outcomes in AF and risk of hospitalization events. Our results underscore the relevance of patient-reported outcomes to clinical adversity and prognosis in AF.

Indexed as

Atrial fibrillationHospitalizationPatient-reported outcomeQuality and Outcomes

Identifiers

PMID34151309
PMCPMC8211119
OpenAlexW3147221643

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.