Evidence map›Paper›PMID 34151275›Full record

ArticleCritical care explorations2021

Time to Lung Volume Stability After Pressure Change During High-Frequency Oscillatory Ventilation.

David G Tingay, Nicholas Kiraly, John F Mills, Peter A Dargaville

Open access · goldAbstract read
In one paragraph

Article in Critical care explorations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Feasibility of lung ultrasound-guided positive end-expiratory pressure adjustment in newborns.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  3. Observational
  4. Article
  5. Observational
  6. Lung ultrasound of the dependent lung detects real-time changes in lung volume in the preterm lamb.Archives of disease in childhood. Fetal and neonatal edition · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

David G Tingay
Nicholas KiralyNeonatal Research, Murdoch Children's Research Institute, Parkville, VIC, Australia.
John F MillsNeonatal Research, Murdoch Children's Research Institute, Parkville, VIC, Australia.
Peter A DargavilleNeonatal Research, Murdoch Children's Research Institute, Parkville, VIC, Australia.
Murdoch Children's Research Institute · AUUniversity of Tasmania · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinicians have little guidance on the time needed before assessing the effect of a mean airway pressure change during high-frequency oscillatory ventilation. We aimed to determine: 1) time to stable lung volume after a mean airway pressure change during high-frequency oscillatory ventilation and 2) the relationship between time to volume stability and the volume state of the lung.

designProspective observational study.

settingRegional quaternary teaching hospital neonatal ICU. PATIENTS: Thirteen term or near-term infants receiving high-frequency oscillatory ventilation and muscle relaxants.

interventionsOne to two cm H MEASUREMENTS AND MAIN

resultsContinuous lung volume measurements (respiratory inductive plethysmography) were made during the mean airway pressure changes. Volume signals were analyzed with a biexponential model to calculate the time to stable lung volume if the model

conclusionsDuring high-frequency oscillatory ventilation, the time to stable lung volume after a mean airway pressure change is variable, often requires more than 10 minutes, and is dependent on the preceding volume state.

Indexed as

high-frequency oscillatory ventilationinfantlung mechanicsmechanical ventilation

Identifiers

PMID34151275
PMCPMC8205213
OpenAlexW3172093958

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.