Evidence map›Paper›PMID 34151271›Full record

ReviewOxford open immunology2021

The emerging role of group 3 innate lymphoid cells in the neonate: interaction with the maternal and neonatal microbiome.

Julie Mirpuri

Open access · goldAbstract readReview
In one paragraph

Review in Oxford open immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Look Who's Talking: Host and Pathogen Drivers ofInternational journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Julie MirpuriDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Suite F3.302, Dallas, TX 75390-9063, USA.ORCID https://orcid.org/0000-0003-4255-3474
Southwestern Medical Center · US

Funding

Mechanisms of maternal high fat diet induced susceptibility to gut inflammation in offspringR01DK121975 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI MIRPURI-HATHIRAMANI, JULIE · 2020 to 2024
$1.8M
NIDDK NIH HHS R01 DK121975
6 · The paper itself

Abstract

Innate lymphoid cells (ILCs) are critical for host defense and are notably important in the context of the newborn when adaptive immunity is immature. There is an increasing evidence that development and function of group 3 ILCs (ILC3) can be modulated by the maternal and neonatal microbiome and is involved in neonatal disease pathogenesis. In this review, we explore the evidence that supports a critical role for ILC3 in resistance to infection and disease pathogenesis in the newborn, with a focus on microbial factors that modulate ILC3 function. We then briefly explore opportunities for research that are focused on the fetus and newborn.

Indexed as

innate lymphoid cellslc3maternalmicrobiomeneonatal

Identifiers

PMID34151271
PMCPMC8208228
OpenAlexW3163602768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.