Evidence map›Paper›PMID 34151208›Full record

ArticleACS pharmacology & translational science2021

14,17,18-Trihydroxy-Eicosatetraenoic Acid: A Novel Pro-Resolving Lipid Mediator from Marine Microalgae.

Hans Jagusch, Markus Werner, Duco Koenis, Jesmond Dalli, Oliver Werz, Georg Pohnert

Open access · greenAbstract read
In one paragraph

Article in ACS pharmacology & translational science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Enhanced COBiotechnology reports (Amsterdam, Netherlands) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Hans JaguschInstitute for Inorganic and Analytical Chemistry, Department of Instrumental Analytics/Bioorganic Analytics, Friedrich Schiller University Jena, Lessingstraße 8, 07743 Jena, Germany.
Markus WernerInstitute of Pharmacy, Department of Pharmaceutical/Medicinal Chemistry, Friedrich Schiller University Jena, Philosophenweg 14, 07743 Jena, Germany.
Duco KoenisWilliam Harvey Research Institute, John Vane Science Centre, Queen Mary University of London, Charterhouse Square, EC1M 6BQ London, United Kingdom.
Jesmond DalliWilliam Harvey Research Institute, John Vane Science Centre, Queen Mary University of London, Charterhouse Square, EC1M 6BQ London, United Kingdom.
Oliver WerzInstitute of Pharmacy, Department of Pharmaceutical/Medicinal Chemistry, Friedrich Schiller University Jena, Philosophenweg 14, 07743 Jena, Germany.ORCID https://orcid.org/0000-0002-5064-4379
Georg PohnertInstitute for Inorganic and Analytical Chemistry, Department of Instrumental Analytics/Bioorganic Analytics, Friedrich Schiller University Jena, Lessingstraße 8, 07743 Jena, Germany.ORCID https://orcid.org/0000-0003-2351-6336
Friedrich Schiller University Jena · DEQueen Mary University of London · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Specialized pro-resolving mediators (SPMs) are enzymatically oxygenated derivatives of polyunsaturated fatty acids that function as central immunoregulators in mammals. Among them are resolvins (Rvs) that stimulate the clearance of harmful stimuli and limit pro-inflammatory processes. Because of their beneficial features and their high potency, SPMs are promising molecules for anti-inflammatory therapy. Besides mammals, also marine algae form lipid mediators such as prostaglandins and leukotrienes. In particular, microalgae are attractive candidates for the production of bioactive high-value metabolites. Here, we identified the diatom

Identifiers

PMID34151208
PMCPMC8205247
OpenAlexW3171993825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.