ArticleJournal of dentistry (Shiraz, Iran)2021
Evaluation of the Relationship between Salivary Lipids, Proteins and Total Antioxidant Capacity with Gingival Health Status in Type-1 Diabetic Children.
Article in Journal of dentistry (Shiraz, Iran), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 8 citations in OpenAlex.
- Implication of serum and salivary albumin tests in the recent oral health related epidemiological studies: A narrative review.The Saudi dental journal · 2024Review
- Changes in salivary biomarkers associated with periodontitis and diabetic neuropathy in individuals with type 1 diabetes.Scientific reports · 2022Article
- Efficacy of nonsurgical periodontal therapy affecting salivary biomarkers in non-diabetic and type 2 diabetic periodontitis patients. An observational study.Journal of oral biology and craniofacial researchArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
statement of the problemAlteration in salivary composition and its effect on the oral cavity in diabetic child patients remains equivocal. PURPOSE: This study was performed to assess the relationship between salivary factors and gingival status in children with type-1 diabetes mellitus (DM). MATERIAL AND
methodIn this cross-sectional study, 120 subjects aged 6-16 years (60 well-controlled and poorly-controlled diabetics and 60 healthy individuals) were examined to determine the gingival index (GI) and plaque index (PI). The unstimulated saliva samples were collected to measure the salivary triglyceride, cholesterol, albumin, α-amylase, total protein levels by the laboratory kits. Total antioxidant capacity and the free radicals scavenger index were measured by the Ferric Reducing Ability Of Plasma (FRAP) and 1,1-Diphenyl-2-picryl-hydrazyl (DPPH) assays, respectively. Data were analyzed by parametric and non-parametric, Pearson correlation, and t tests at a 5% error level.
resultsGI of diabetics was significantly higher than that of healthy individuals (1.51± 0.71 and 0.9±0.81, respectively,
conclusionMore gingival inflammation and salivary α-amylase activity and lower level of salivary lipids, albumin, and total proteins were found in diabetic patients, but there was no association between the level of lipids, proteins, and the total antioxidant capacity of saliva with periodontal health indicators in patients with DM and healthy individuals.
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