Evidence map›Paper›PMID 34150806›Full record

ArticleFrontiers in medicine2021

Investigation of Coagulation Biomarkers to Assess Clinical Deterioration in SARS-CoV-2 Infection.

Paul Billoir, Kevin Alexandre, Thomas Duflot, Maxime Roger, Sébastien Miranda, Odile Goria, Luc Marie Joly, Mathieu Demeyere, Guillaume Feugray, Valery Brunel and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  13. Clinical use of thrombin generation assays.Journal of thrombosis and haemostasis : JTH · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Paul BilloirNormandie Univ, UNIROUEN, INSERM U1096, CHU Rouen, Vascular Hemostasis Unit, Rouen, France.
Kevin AlexandreNormandie Univ, UNIROUEN, EA2656, CHU Rouen, Department of Infectious Diseases, Rouen, France.
Thomas DuflotNormandie Univ, UNIROUEN, INSERM U1096, CHU Rouen, Department of Pharmacology, Rouen, France.
Maxime RogerCHU Rouen, Department of Pneumology, Rouen, France.
Sébastien MirandaF-CRIN INNOVTE, St-Étienne, France.
Odile GoriaCHU Rouen, Department of Gastroenterology and Hepatology, Rouen, France.
Luc Marie JolyDepartment of Emergency Medicine, Normandie Univ, UNIROUEN, CHU Rouen, Rouen, France.
Mathieu DemeyereCHU Rouen, Department of Radiology, Rouen, France.
Guillaume FeugrayNormandie Univ, UNIROUEN, INSERM U1096, CHU Rouen, Vascular Hemostasis Unit, Rouen, France.
Valery BrunelDepartment of General Biochemistry, CHU Rouen, Rouen, France.
Manuel EtienneNormandie Univ, UNIROUEN, EA2656, CHU Rouen, Department of Infectious Diseases, Rouen, France.
Véronique Le Cam DuchezNormandie Univ, UNIROUEN, INSERM U1096, CHU Rouen, Vascular Hemostasis Unit, Rouen, France.
Université de Rouen Normandie · FRCentre Hospitalier Universitaire de Rouen · FRInserm · FRNormandie Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since December 2019, a pandemic caused by a new coronavirus has spread to more than 170 countries around the world. Worsening infected patients requiring intensive care unit (ICU) admission associated with 30% of mortality. A part of worsening is induced by hemostasis deregulation. The aim of this study was to investigate the association of coagulation activation in COVID-19 progression. Thirty-five of the 99 patients got clinically worse. The final model of the logistic regression analysis revealed that O

Indexed as

COVID-19fibrinogenhypercoagulabilityintensive carethrombin generation

Identifiers

PMID34150806
PMCPMC8211892
OpenAlexW3168693390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.