ReviewFrontiers in cell and developmental biology2021
Organ-Specific Branching Morphogenesis.
Review in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Review
- Developmentally inspired synthetic kidney engineering.Nature biotechnology · 2026Review
- Synthetic budding morphogenesis by optogenetic receptor tyrosine kinase signaling.bioRxiv : the preprint server for biology · 2026Article
- Timing of NAD Deficiency During Organogenesis Dictates Defect Type and Penetrance.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Development of a compartmentalized silk fibroin-reinforced GelMA hydrogel platform for kidney-inspired tissue engineering.Frontiers in bioengineering and biotechnology · 2026Article
- Epithelial cell shape changes contribute to regulation of ureteric bud branching morphogenesis.The FEBS journal · 2025Article
- EGF receptor in organ development, tissue homeostasis and regeneration.Journal of biomedical science · 2025Review
- Embryonic Mammary Gland Morphogenesis.Advances in experimental medicine and biology · 2025Review
- Breast Morphogenesis: From Normal Development to Cancer.Advances in experimental medicine and biology · 2025Review
- Histology Atlas of the Developing Mouse Respiratory System From Prenatal Day 9.0 Through Postnatal Day 30.Toxicologic pathology · 2024Review
- Mesenchyme instructs growth while epithelium directs branching in the mouse mammary gland.eLife · 2024Article
- Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner.Developmental cell · 2024Article
- Spatially coordinated cell cycle activity and motility govern bifurcation of mammary branches.The Journal of cell biology · 2023Article
- Inflationary theory of branching morphogenesis in the mouse salivary gland.Nature communications · 2023Article
- Independent control over cell patterning and adhesion on hydrogel substrates for tissue interface mechanobiology.iScience · 2023Article
- Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids.Nature communications · 2022Article
- Wnt5a-Vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions.PLoS biology · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A common developmental process, called branching morphogenesis, generates the epithelial trees in a variety of organs, including the lungs, kidneys, and glands. How branching morphogenesis can create epithelial architectures of very different shapes and functions remains elusive. In this review, we compare branching morphogenesis and its regulation in lungs and kidneys and discuss the role of signaling pathways, the mesenchyme, the extracellular matrix, and the cytoskeleton as potential organ-specific determinants of branch position, orientation, and shape. Identifying the determinants of branch and organ shape and their adaptation in different organs may reveal how a highly conserved developmental process can be adapted to different structural and functional frameworks and should provide important insights into epithelial morphogenesis and developmental disorders.
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