Evidence map›Paper›PMID 34150670›Full record

ArticleFrontiers in cellular and infection microbiology2021

Protein and Microbial Biomarkers in Sputum Discern Acute and Latent Tuberculosis in Investigation of Pastoral Ethiopian Cohort.

Milkessa HaileMariam, Yanbao Yu, Harinder Singh, Takele Teklu, Biniam Wondale, Adane Worku, Aboma Zewude, Stephanie Mounaud, Tamara Tsitrin, Mengistu Legesse and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  5. Autophagy andFrontiers in cellular and infection microbiology · 2026
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  12. HBFP: a new repository for human body fluid proteome.Database : the journal of biological databases and curation · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Milkessa HaileMariamAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
Yanbao YuJ. Craig Venter Institute, Rockville, MD, United States.
Harinder SinghJ. Craig Venter Institute, Rockville, MD, United States.
Takele TekluAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
Biniam WondaleAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
Adane WorkuAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
Aboma ZewudeAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
Stephanie MounaudJ. Craig Venter Institute, Rockville, MD, United States.
Tamara TsitrinJ. Craig Venter Institute, Rockville, MD, United States.
Mengistu LegesseAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
Ameni GobenaAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
Rembert PieperJ. Craig Venter Institute, Rockville, MD, United States.
Addis Ababa University · ETJ. Craig Venter Institute · USArba Minch University · ETUniversity of Gondar · ET

Funding

Ethiopia-Emory TB Research Training ProgramD43TW009127 · FIC · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Kidist Bobosha · 2013 to 2026
$3.4M
Systems Biology for Molecular Analysis of Tuberculosis in EthiopiaU01HG007472 · NHGRI · ADDIS ABABA UNIVERSITY · PI AMENI, GOBENA · 2013 to 2016
$1.2M
FIC NIH HHS D43 TW009127NHGRI NIH HHS U01 HG007472
6 · The paper itself

Abstract

Differential diagnosis of tuberculosis (TB) and latent TB infection (LTBI) remains a public health priority in high TB burden countries. Pulmonary TB is diagnosed by sputum smear microscopy, chest X-rays, and PCR tests for distinct

Indexed as

Latent TuberculosisMycobacterium tuberculosisBiomarkersEthiopiaHumansProteomicsReceptors, GABARNA, Ribosomal, 16SSputumBiomarkersReceptors, GABARNA, Ribosomal, 16STSPO protein, humanacute phase responseLTBImicrobiomeprotein biomarkerRothiasputumtuberculosisα-1-acid glycoprotein

Identifiers

PMID34150670
PMCPMC8212885
OpenAlexW3172993978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.